Scleroprotein of an adeno-associated virus with modified...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

Reexamination Certificate

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C435S091330, C435S236000

Reexamination Certificate

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10031187

ABSTRACT:
The invention relates to a scleroprotein of an adeno-associated virus which contains at least one mutation. Said mutation causes the chromatographic properties to be modified. The invention also relates to the production of said scleroprotein and the use thereof.

REFERENCES:
patent: 5276136 (1994-01-01), Skubitz et al.
patent: 6491907 (2002-12-01), Rabinowitz et al.
patent: 2001/0031463 (2001-10-01), Kleinschmidt et al.
patent: 2002/0192823 (2002-12-01), Bartlett
patent: WO95/23867 (1995-09-01), None
patent: WO 95/23867 (1995-09-01), None
patent: WO 96/00587 (1996-01-01), None
patent: WO96/00587 (1996-01-01), None
patent: WO97/08298 (1997-03-01), None
patent: WO 97/38723 (1997-10-01), None
patent: WO97/38723 (1997-10-01), None
patent: WO99/67393 (1999-12-01), None
patent: WO 99/67393 (1999-12-01), None
Hoque et al., Chimeric Virus-like Particle Formation of Adeno-Associated Virus (Biochemical and Biophysical Research Communications 266, 371-376, 1999.
Yang et al., Developemant of Novel Cell Surface CD34-Targeted Recombinant Adenoassociated Virus Vectors for Gene Therapy (Human Gene Therapy 9:1929-1937, Sep. 1, 1998.
Spear et. al., Evidence for Two Nucleotide Sequences Orientations within the Terminal Repetition of Adeno-Associated Virus DNA (Journal of Virology, Nov. 1977, p. 627-634).
Ruffing et al., Mutations in the carboxy trminus of adeno-associated virus 2 capsid proteins affect viral infectivity: lack of an RGD integrin-binding motif. (Journal of General Virology, Dec. 1994;75 (Pt 12):3385-3392).
Wistuba et al., “Intermediates of Adeno-Associated Virus Type 2 Assembly: Identification of Soluble Complexes Containing Rep and Cap Proteins,”Journal of Virology69:5311-5319 (1995).
Aumailley et al., “Identification of the Arg-Gly-Asp Sequence in Laminin A Chain as a Latent Cell-Binding Site Being Exposed in Fragment P1,”FEBS262:82-86 (1990).
Bartlett et al., “Targeted Adeno-Associated Virus Vector Transduction of Nonpermissive Cells Mediated by a Bispecific F (ab'γ)2Antibody,”Nature Biotechnology17:181-186 (1999).
Chiorini et al., “High-Efficiency Transfer of the T Cell Co-Stimulatory Molecule B7-2 to Lymphoid Cells Using High Titer Recombinant Adeno-Associated Virus Vectors,”Human Gene Therapy6:1531-1541 (1995).
Cosset et al., “Targeting Retrovirus Entry,”Gene Therapy3:946-956 (1996).
Douglas et al., “Targeted Gene Delivery by Tropism-Modified Adenoviral Vectors,”Nature Biotechnology14:1574-1578 (1996).
Girod et al., “Genetic Capsid Modifications Allow Efficient Re-Targeting of Adeno-Associated Virus Type 2,”Nature Medicine5:1052-1056 (1999).
Hermonat et al., “Genetics of Adeno-Associated Virus: Isolation and Preliminary Characterization of Adeno-Associated Virus Type 2 Mutants,”Journal of Virology51:329-339 (1984).
Kotin, “Prospects for the Use of Adeno-Associated Virus as a Vector for Human Gene Therapy,”Human Gene Therapy5:793-801 (1994).
Krasnykh et al., “Generation of Recombinant Adenovirus Vectors with Modified Fibers for Altering Viral Tropism,”Journal of Virology70:6839-6846 (1996).
Luo, “Preliminary X-Ray Crystallographic Analysis of Canine Parvovirus Crystals,”J. Mol. Biol.200:209-211 (1988).
Muzyczka, “Use of Adeno-Associated Virus as a Genaral Transduction Vector for Mammalian Cells,”Current Topics in Microbiology and Immunology158:98-129 (1992).
Ohno et al., “Cell-Specific Targeting of Sindbis Virus Displaying IgG-Binding Domains of Protein A,”Nature Biotechnology5:763-767 (1997).
Ruffing et al., “Mutations in the Carboxy Terminus of Adeno-Associated Virus 2 Capsid Proteins Affect Viral Infectivity: Lack of an RGD Integrin-Binding Motif,”Journal of General Virology75:3385-3392 (1994).
Ruffing et al., “Assembly of Viruslike Particles by Recombinant Structural Proteins of Adeno-Associated Virus Type 2 in Insect Cells,”Journal of Virology66:6922-6930 (1992).
Rutledge et al., “Infectious Clones and Vectors Derived From Adeno-Associated Virus (AAV) Serotypes Other Than AAV Type 2,”Journal of Virology72:309-319 (1998).
Srivastava et al., “Nucleotide Sequence and Organization of the Adeno-Associated Virus 2 Genome,”Journal of Virology45:555-564 (1983).
Steinbach et al., “Assembly of Adeno-Associated Virus Type 2 Capsids in Vitro,”Journal of General Virology78:1453-1462 (1997) (Abstract).
Valsesia-Wittmann et al., “Modifications in the Binding Domain of Avian Retrovirus Envelope Protein To Redirect the Host Range of Retroviral Vectors,”Journal of Virology68:4609-4619 (1994).
Wickham et al., “Increased in Vitro and In Vivo Gene Transfer by Adenovirus Vectors Containing Chimeric Fiber Proteins,”Journal of Virology71:8221-8229 (1997).
Wistuba et al., “Subcellular Compartmentalization of Adeno-Associated Virus Type 2 Assembly,”Journal of Virology71:1341-1352 (1997).
Wu et al., “The Canine Parvovirus Empty Capsid Structure,”Mol. Biol.233:231-244 (1993).
Yang et al., “Development of Novel Cell Surface CD34-Targeted Recombinant Adenoassociated Virus Vectors for Gene Therapy,” Human Gene Therapy 9:1929-1937 (1998).
Chapman et al., “Structure, Sequence, and Function Correlations Among Parvoviruses,”Virology194:491-508 (1993).
Luo et al., “Preliminary X-Ray Crystallographic Analysis of Canine Parovirus Crystals,”J. Mol. Biol.200:209-211 (1988).
Muzyczka, “Use of Adeno-Associated Virus as a General Transduction Vector for Mammalian Cells,”Current Topics in Microbiology and Immunology158:97-129 (1992).
Nimako et al., “Human Papillomavirus-Specific Cytotoxic T Lymphocytes in Patients with Cervical Intraepithelial Neoplasia Grade III,”Cancer Research57:4855-4861 (1997).
Steinbach et al., “Assembly of Adeno-Associated Virus Type 2 Capsids in vitro,”Journal of General Virology78:1453-1462 (1997) (Abstract).
Stevenson et al., “Selective Targeting Human Cells by a Chimeric Adenovirus Vector Containing a Modified Fiber Protein,”Journal or Virology71:4782-4790 (1997).
Tarpey et al., “Human Cytotoxic T Lymphocytes Stimulated by Endogenously Processed Human Papillomavirus Type 11 E7 Recognize a Peptide Containing a HLA-A2 (A*0201) Motif,”Immunology81:222-227 (1994).
Tsao et al., “The Three-Dimensional Structure of Canine Parvovirus and Its Functional Implications,”Science251:1456-1464 (1991).
Wickham et al., (1996), “Adenovirus Targeted to Heparan-containing Receptors Increases its Gene Delivery Efficiency to Multiple Cell Types,”Nat. Biotechnol., 14:1570-1573.
Wu et al., “The Canine Parvovirus Empty Capsid Structure,”J. Mol. Biol.233:231-244 (1993).
Anderson, “Human Gene Therapy,”Nature392:25-30 (1998).
Asokan et al., “AAV Does the Shuffle,”Nature Biotechnology24:158-160 (2006).
Buning et al., “Receptor Targeting of Adeno-Associated Virus Vectors,”Gene Therapy10:1142-1151 (2003).
Grifman et al., Incorporation fo Tumor-Targeting Peptides into Recombinant Adeno-Associated Virus Capsids,Molecular Therapy3:964-975 (2001).
Hoque et al., “Nuclear Transport of the Major Capsid Protein is Essential for Adeno-Associated Virus Capsid Formation,”Journal of Virology73:7912-7915 (1999).
Huttner et al., “Genetic Modifications of the Adeno-Associated Virus Type 2 Capsid Reduce the Affinity and the Neutralizing Effects of Human Serum Antibodies,”Gene Therapy10:2139-2147 (2003).
Kmiec, “Gene Therapy,”American Scientist87:240-247 (1999 ).
Maass et al., “Recombinant Adeno-Associated Virus for the Generation of Autologous, Gene-Modified Tumor Vaccines: Evidence for a High Transduction Efficiency into Primary Epithelial Cancer Cells,”Human Gene Therapy9:1049-1059 (1998).
Maheshri et al., “Directed Evolution of Adeno-Associated Virus Yields Enhanced

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