Schiff's base derivatives of thienamycin

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...

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2602452, 26032612R, 26032625, 424250, 424251, 424263, 424269, 424270, 424272, 424273R, 542416, 544239, 544316, 544355, 546272, 548336, A61K 3140, C07D48704

Patent

active

041721446

ABSTRACT:
Disclosed are Schiff's base derivatives of the antibiotic thienamycin, which has the following structure: ##STR1## Such compounds and their pharmaceutically acceptable salt, ester and amide derivatives are useful as antibiotics. Also disclosed are processes for the preparation of such derivatives, pharmaceutical compositions comprising such derivatives, and methods of treatment comprising administering such derivatives and compositions when an antibiotic effect is indicated.

REFERENCES:
patent: 3950357 (1976-04-01), Keehan et al.
Derwent Abstract, 40279y (Nov. 19, 1976).

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