Schiff base derivatives of ruthenium and osmium olefin metathesi

Details Schiff base derivatives of ruthenium and osmium olefin metathesi Schiff base derivatives of ruthenium and osmium olefin metathesi

1998-11-12

1999-11-02

Nazario-Gonzalez, Porfirio

Organic compounds -- part of the class 532-570 series

Organic compounds

Heavy metal containing

556 33, 556137, 502155, 502162, 526171, 526172, 526183, 526190, 526280, 526281, 26417123, 26417128, C07F 1500, C08F 480

Patent

active

059773936

ABSTRACT:
The present invention generally relates to ruthenium and osmium carbene catalysts for use in olefin metathesis reactions. More particularly, the present invention relates to Schiff base derivatives of ruthenium and osmium carbene catalysts and methods for making the same. The inventive catalysts are generally prepared by the treatment of unmodified catalysts with the salts of the desired Schiff base ligands, in which an anionic and a neutral electron donating ligands of the unmodified catalysts are simultaneously replaced. The Schiff base derivatives of the ruthenium and osmium carbene catalysts show unexpectedly improved thermal stability while maintaining high metathesis activity, even in polar protic solvents. Although the inventive catalysts may be used in all metathesis reactions, use of these catalysts for ring-closing metathesis ("RCM") reactions is particularly preferred.

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