Scanning confocal microscope

Optical: systems and elements – Compound lens system – Microscope

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359386, 359389, G02B 2100, G02B 2106

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057609500

ABSTRACT:
A scanning confocal microscope optical system overcomes the difficulties of previous devices and can be used in diagnostic applications that are inaccessible to previous devices. The optical system for forming an image of a subject illuminated by light from an illumination system includes a Nipkow disk that is perpendicular to a light propagation path and that has a surface upon which a plurality of pinholes are distributed substantially symmetrically about an axis perpendicular to the surface of the disk. The system further includes components for projecting an image of a first set of the pinholes onto a second set of the pinholes, the image being formed of light transmitted by the first set of the pinholes when the first set is illuminated by light that impinges on a first side of the disk. The system further includes a collective lens and a first objective lens for focussing light transmitted by the second set of the pinholes onto the subject and for collecting light reflected by the subject. The first objective lens has a large numerical aperture and light reflected by the subject passes through the second set of pinholes. Finally, the system may include a device for spinning the Nipkow disk about the axis.

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