Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1994-09-19
1997-07-08
Eisenschenk, Frank C.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530402, 436533, 436532, C07K 1706, G01N 3353, G01N 33543
Patent
active
056462565
ABSTRACT:
The present invention is directed to methods for using reagents to generate and stabilize thiols derived from thiol precursors in order to permit more effective reactions with thiol-reactive substances such as liposomes, proteins and antibodies. These methods provide greatly improved conjugates for utilization in various in vivo and in vitro applications.
REFERENCES:
patent: 5324650 (1994-06-01), Obzamsky et al.
Neurochem. Res., Grossfeld et al., 1984, 9(7):947.
Duncan et al., Anal. Biochem., 1983, 132:68.
Moore Samuel L.
Readio Josephine
Rutner Herman
Shackelford William
Becton Dickinson and Company
Eisenschenk Frank C.
Weintraub Bruce S.
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