SARS-CoV-specific B-cell epitope and applications thereof

Details SARS-CoV-specific B-cell epitope and applications thereof SARS-CoV-specific B-cell epitope and applications thereof

2004-09-21

2010-06-22

Parkin, Jeffrey S (Department: 1648)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

C424S184100, C424S185100, C424S204100, C424S221100, C530S300000

Reexamination Certificate

active

07740858

ABSTRACT:
Disclosed is SARS-CoV-specific B-cell epitope and applications thereof. The epitopes are peptides and can either be expressed in phages or synthesized to diagnose SARS patients accurately. High sensitivity and specificity of the serologic detection are achievable by using a plurality of SARS-CoV-specific B-cell epitope-based peptides. Therefore, the peptides can be applied to SARS diagnosis and have potentials to be immunogens for producing antibodies against SARS.

REFERENCES:
patent: 2005/0100883 (2005-05-01), Wang et al.
patent: 2005/0106563 (2005-05-01), Huang et al.
patent: 1475571 (2004-02-01), None
Miura et al. Interaction of Ash/Grb-2 via its SH3 domains with neuron-specific p150 and p65. Biochemical Journal 1996, vol. 316, pp. 639-645.
Wang et al. Assessment of Immunoreactive Synthetic Peptides from the Structural Proteins of Severe Acute Respiratory Syndrome Coronavirus. Clinical Chemistry 2003, vol. 49, No. 12, p. 1989-1996.
Rota et al. Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome. Science 2003, vol. 300, No. 5624, p. 1394-1399.
I-Ju Liu et al., Disease-Specific B Cell Epitopes for Serum Antibodies from Patients with Severe Acute Respiratory Syndrome (SARS) and Serologic Detection of SARS Antibodies by Epitope-Based Peptide Antigens,The Journal of Infectious Diseases2004; 190:797-809.

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