Saquinavir derivatives useful in immunoassay

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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Details

C530S403000, C530S409000, C530S809000, C435S070210, C435S430100, C546S144000, C436S529000, C436S815000

Reexamination Certificate

active

06992177

ABSTRACT:
Analogs of saquinavir functionalized at the quinoline portion of the molecule are described. These include pyridyl analogs (replacing the quinoline ring) with a functional handle out of the ring allowing for elaboration with linkers terminated by a functional group such as an activated ester which are useful for attaching the molecule to other entities such as proteins, polysaccharides, and the like. Analogs of saquinavir derivatized out of the quinoline ring are also described.

REFERENCES:
patent: 5508407 (1996-04-01), Kaldor et al.
patent: 5679688 (1997-10-01), Grobelny
patent: 2004/0127689 (2004-07-01), Sigler et al.
patent: 1207394 (2002-05-01), None
patent: WO 93/04043 (1993-03-01), None
patent: WO 93/18006 (1993-09-01), None
patent: WO 03/006506 (2003-01-01), None

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