Sandwich immunoassay for determination of total monoclonal IGG

Details Sandwich immunoassay for determination of total monoclonal IGG Sandwich immunoassay for determination of total monoclonal IGG

1988-01-29

1991-01-08

Kepplinger, Esther L.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

436538, 436548, 436815, G01N 33543, G01N 33577

Patent

active

049835300

ABSTRACT:
A sandwich immunoassay for determining total monoclonal IgG content in samples of purified IgG, cell culture medium and ascites fluid is provided based on the utilization of anti-light-chain IgG antibodies as both capture and label antibodies.

REFERENCES:
patent: 4486530 (1984-12-01), David et al.
patent: 4618589 (1986-10-01), Jefferis et al.
Lowe et al., Immunology, vol. 42, 649 (1981), pp. 649-659.
Axiak et al., Journal of Immunological Methods, vol. 99, 141 (1987), pp. 141-147.
Springer, T. et al., Hybridoma 1 No. 3:257-273 (1982).

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