Liquid purification or separation – With means to add treating material – Chromatography
Reexamination Certificate
2006-07-11
2006-07-11
Therkorn, Ernest G. (Department: 1723)
Liquid purification or separation
With means to add treating material
Chromatography
C210S656000, C210S143000, C422S070000, C422S105000, C422S105000
Reexamination Certificate
active
07074327
ABSTRACT:
Systems and methods are provided for preparing samples for chromatographic separations and then chromatographically separating the prepared samples, preferably in a high-throughput fashion utilizing multiple parallel first (fluid) processing regions in fluid communication with multiple parallel second (fluid) processing regions wherein the each second processing region includes a chromatography column. One or more common fluid supplies may be utilized in each of the sample preparation and separation steps to minimize the number of requisite fluid connections and external components such as pumps, reservoirs, pulse dampers, flow controllers, and the like.
REFERENCES:
patent: 4946795 (1990-08-01), Gibbons et al.
patent: 5030418 (1991-07-01), Miyata
patent: 5478751 (1995-12-01), Oosta et al.
patent: 5658413 (1997-08-01), Kaltenbach et al.
patent: 5690763 (1997-11-01), Ashmead et al.
patent: 5731212 (1998-03-01), Gavin et al.
patent: 5783450 (1998-07-01), Yoshida et al.
patent: 5824204 (1998-10-01), Jerman
patent: 5839467 (1998-11-01), Saaski et al.
patent: 5863502 (1999-01-01), Southgate et al.
patent: 5872010 (1999-02-01), Karger et al.
patent: 5928880 (1999-07-01), Wilding et al.
patent: 6004450 (1999-12-01), Northrup et al.
patent: 6043080 (2000-03-01), Lipshutz et al.
patent: 6063283 (2000-05-01), Shirota et al.
patent: 6117396 (2000-09-01), Demers
patent: 6240790 (2001-06-01), Swedberg et al.
patent: 6296771 (2001-10-01), Miroslav
patent: 6312888 (2001-11-01), Wong et al.
patent: 6331439 (2001-12-01), Cherukuri et al.
patent: 6408878 (2002-06-01), Unger et al.
patent: 6416716 (2002-07-01), Shukla et al.
patent: 6436292 (2002-08-01), Petro
patent: 6437345 (2002-08-01), Bruno-Raimondi et al.
patent: 6458273 (2002-10-01), Krakover et al.
patent: 6461515 (2002-10-01), Safir et al.
patent: 6485690 (2002-11-01), Pfost et al.
patent: 6494614 (2002-12-01), Bennett et al.
patent: 6532978 (2003-03-01), Müller-Kuhrt et al.
patent: 6581441 (2003-06-01), Paul
patent: 6585939 (2003-07-01), Dapprich
patent: 6603546 (2003-08-01), Barbieri et al.
patent: 6613581 (2003-09-01), Wada et al.
patent: 6635226 (2003-10-01), Tso et al.
patent: 6637463 (2003-10-01), Lei et al.
patent: 6664104 (2003-12-01), Pourahmadi et al.
patent: 6812030 (2004-11-01), Ozbal et al.
patent: 6936167 (2005-08-01), Hobbs et al.
patent: 2001/0013494 (2001-08-01), Maiefski et al.
patent: 2002/0033337 (2002-03-01), Ausserer et al.
patent: 2002/0048536 (2002-04-01), Bergh et al.
patent: 2002/0068357 (2002-06-01), Mathies et al.
patent: 2002/0068366 (2002-06-01), LaDine et al.
patent: 2002/0158022 (2002-10-01), Huang et al.
patent: 2002/0199094 (2002-12-01), Strand et al.
patent: 2003/0094415 (2003-05-01), Tanimura
patent: 2003/0118486 (2003-06-01), Zhou et al.
patent: 2003/0150792 (2003-08-01), Koehler et al.
patent: 2003/0150806 (2003-08-01), Hobbs et al.
patent: 2003/0162304 (2003-08-01), Dority et al.
patent: 2003/0200794 (2003-10-01), Paul
patent: 2003/0230524 (2003-12-01), Soga et al.
patent: 2004/0158433 (2004-08-01), Wimschneider et al.
patent: 2005/0048669 (2005-03-01), Hobbs et al.
patent: 0 545 284 (1993-06-01), None
patent: 0 686 848 (1995-12-01), None
patent: WO 98/04909 (1998-02-01), None
patent: WO 98/35376 (1998-08-01), None
patent: WO 00/51720 (2000-09-01), None
patent: WO 00/72970 (2000-12-01), None
patent: WO 00/76662 (2000-12-01), None
patent: WO 01/09598 (2001-02-01), None
patent: WO 01/32930 (2001-05-01), None
patent: WO 02/22250 (2002-03-01), None
patent: WO 02/29106 (2002-04-01), None
patent: WO 02/056006 (2002-07-01), None
patent: WO 03/002226 (2003-01-01), None
Development of a high-pressure gradient pumping system for parrallel liquid chromatography/mass spectrometry for the analysis of combinatorial libaries, “Rapid Communications in Mass Spectrometry,” 2001, 15, 1244-1249, Letter to the Editor, John Wiley & Sons, Ltd.
Fang, Liling et al.,High-throughput liquid chromatograpohy Ultraviolet.mass spectrometric analysis of combinatorial libraries using an eight-channel multiplexed electrospray time-of-flight mass spectrometer, “Rapid Communications in Mass Spectrometry,” 2002; 16:1440-1447.
Manica, Drew P. et al., “Dual Electrochemical and Optical Detection on a Microfabricated Electrophoresis Chip,”Micro Total Analysis Systems, J.M. Ramsey and A. van den Berg (eds.), 2001, Kluwer Academic Publishers, the Netherlands, pp. 262-264.
Zweigenbaum, Jerry et al.,High-Throughput Bioanalytical LC/MS/MS Determination of Benzodiazepines in Human Urine: 1000 Samples per 12 Hours, “Analytical Chemistry,” vol. 71, No. 13, Jul. 1, 1999, pp. 2294-2300.
Jacobson, S.C. et al., “Micro-Scale Liquid Phase Sensors: Chromatography on a Chip,” Abstracts of Papers, Part 1, American Chemical Society, 207thACS National Meeting, Mar. 13-17, 1994, San Diego, CA.
Broyles, Scott B. et al., “Sample Concentration and Separation on Microchips,”Micro Total Analysis Systems, J.M. Ramsey and A. van den Berg (eds.), 2001, Kluwer Academic Publishers, the Netherlands, pp. 537-538.
Wagner, Knut et al.,An Automated On-Line Multidimensional HPLC System for Protein and Peptide Mapping with Integrated Sample Preparation, “Analytical Chemistry,” vol. 74, No. 4, Feb. 15, 2002, pp. 809-820.
Berna, M. et al.,Collection Storage, and Filtration of in Vivo Study Samples Using 96-Well Filter Plates To Facilitate Automated Sample Preparation and LC/MS.MS Analysis, “Analytical Chemistry,” vol. 74, No. 5, Mar. 1, 2002, pp. 1197-1201.
Grodzinski, Piotr Dr., “Development of Plastic Microfluidic Devices for Sample Preparation,” BioMEMS 2000, Presentation, Columbus, Ohio, Sep. 24, 2000, Motorola Labs.
Taylor, M.T. et al., “Fully Automated Sample Preparation for Pathogen Detection Performed in a Microfludic Cassette,”Micro Total Analysis Systems, J.M. Ramsey and A. van den Berg (eds.), 2001, pp. 670-672, Kluwer Academic Publishers, The Netherlands.
Sjölander, Stefan et al.,Integrated Fluid Handling System for Biomolecular Interaction Analysis, “Analytical Chemistry,” vol. 63, No. 20, Oct. 15, 1991, pp. 2338-2345,
Palm, Anders et al., “Integrated Sample Preparation and MALDI MS on a disc,”Micro Total Analysis Systems, J.M. Ramsey and A, van den Berg (eds.), 2001, pp. 216-218, Kluwer Academic Publishers, The Netherlands.
Khandurina, Julia et al.,Micropreparative Fraction Collection in Microfluidic Devices, “Analytical Chemistry,” vol. 74, No. 7, Apr. 1, 2002, pp. 1737-1740.
Wang, Xuan-Qi et al., “Polymer-Based Electrospray Chips for Mass Spectrometry,” 1997, California Institute of Technology, Pasadena, CA. [publication source unknown]/
Yin, Hongfeng et al., “A polymeric microfluidic device with integrated mass-spectrometer interface,” 2002, Aligent Laboratories, Palo Alto, CA [publication source unknown].
Kuwano, Hiroki et al., “Research and Development of Microsystems,” 1996, NTT Integrated Information & Energy Systems Laboratories.
Shediac, Renée et al.,Reversed-phase electrochromatography of amino acids and peptides using porous polymer monoliths, “Journal of Chromatography A,” 925 (2001) 251-263, Elsevier Science B.V.
Bochner, BR,Sleuthing Out Bacterial Identities, “Nature,” 1989, vol.: No. 6220, pp. 157-158.
Lesney. Mark S. et al.,Solid-Phase Attraction, “Today's Chemist at Work,” Feb. 2002, American Chemical Society, pp. 46-50.
Tan, Aimin et al.,Chip-Based-Phase Extraction Pretreatment for Direct Electrospray Mass Spectrometry Analyis Using an Array of Monolithic Columns in a Polymeric Substrate, “Analytical Chemistry,” vol. 75, No. 20 Oct. 15, 2003, pp. 5504-5511.
Sato Kiichi et al., “Integrated Immunoassay System Using Multichannel Microchip for Simultaneous Determination,”Micro Total Analysis Systems, J.M. Ramsey and A. van den Berg (eds.), 2001, 511-512, Kluwer Acedemic Publishers, The Netherlands.
Norris, Ann M. et al., “Silicone
Dantsker Eugene
Karp Christoph D.
Lee Mike S.
O'Connor Stephen D.
Vajjhala Surekha
Gustafson Vincent K.
Intellectual Property / Technology Law
Nanostream, Inc.
Therkorn Ernest G.
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