Chemistry: molecular biology and microbiology – Apparatus – Bioreactor
Patent
1992-02-25
1993-07-13
Johnston, Jill A.
Chemistry: molecular biology and microbiology
Apparatus
Bioreactor
435287, 435292, 435294, 435 31, 436179, 436180, 422 99, C12M 128
Patent
active
052273032
ABSTRACT:
There is disclosed an automated system for testing the sterility of products intended for human health administration or for human consumption. The system permits a plurality of samples of a product to be concurrently tested. To accomplish this, the system includes a novel apparatus for thoroughly mixing therein a plurality of product samples to assure that a statistically meaningful representation of product samples are subjected to sterility testing. The system is arranged so that multiple samples of a product to be tested are deposited in the mixing apparatus after which the mixed samples are conveyed to testing canisters along with appropriate growth media to determine that the product is sterile or that the product is free from microbial contamination.
REFERENCES:
patent: 4036698 (1977-07-01), Bush et al.
patent: 4351900 (1982-09-01), Lemonnier
patent: 4397945 (1983-08-01), Lemonnier
patent: 4640777 (1987-02-01), Lemonnier
patent: 4863868 (1989-09-01), Holley
Erdman George R.
Fischer Douglas C.
Caruso Charles M.
Johnston Jill A.
Le Long V.
Merck & Co. , Inc.
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