Chemistry: analytical and immunological testing – Including sample preparation – Dilution
Patent
1984-12-03
1986-11-25
Lacey, David L.
Chemistry: analytical and immunological testing
Including sample preparation
Dilution
436162, 436165, 422 56, 422 59, 422 61, 422 70, 422100, 7386454, 7386472, 7386491, G01N 110, G01N 148
Patent
active
046249290
ABSTRACT:
A device is disclosed for collecting a liquid sample and diluting the liquid sample by virtue of being adapted for use with a container having a volume of diluting liquid. The device comprises a housing adapted for mating with the container where the mated housing and container form a chamber. A bibulous pad is attached to the housing for collecting a predetermined amount of a liquid sample. Additionally, the device, when used with the container, creates a pressure differential between the interior of the housing and the chamber. The pressure differential is sufficient to move a predetermined volume of the diluting liquid through the bibulous pad and into the housing. The device can be used for assaying for a component of a sample. The device has particular use in immunochromatography and for convenience can also contain a strip of bibulous material confined in the housing. In a method for collecting a liquid sample and subsequently diluting the sample with a predetermined volume of a liquid, the sample is collected on an bibulous pad at the base of a housing. The pad is designed to absorb a predetermined amount of the sample. Next, a pressure differential is created between the housing and a container having a volume of diluting liquid to cause a predetermined volume of the liquid to pass through the pad and into the housing.
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Lacey David L.
Leitereg Theodore J.
Syntex (U.S.A.) Inc.
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