Sample collection and transport fluid composition

Details Sample collection and transport fluid composition Sample collection and transport fluid composition

1988-09-15

1990-04-24

Wax, Robert A.

Chemical apparatus and process disinfecting, deodorizing, preser

Process disinfecting, preserving, deodorizing, or sterilizing

Process of storage or protection

435 1, 436 18, 436 65, 436176, 436826, 530850, B01J 1118, G01N 100, A01N 102

Patent

active

049198890

ABSTRACT:
Sensitive proteins in human biological secretion samples are preserved by dispersing them in an aqueous solution containing from 0.05 to 0.5M of a buffer which is effective to maintain the solution pH within the range of from 6.5 to 8.0; from 0.1 to 10 wt. % of a non-immune animal protein selected from the group consisting of albumin, ovalbumin, casein, glycoprotein and mixtures thereof; from 40 to 2000 kallikrein units/mL of an enzyme inhibitor of trypsin, chymotrypsin, kallikrein or plasmin; and from 0.01 to 0.1 wt. % of a bacteriostatic agent. The solution preferably also contains from 5 .mu.M to 1 mM of a protease inhibitor; and from 1 to 10 mM of a chelating agent. Optimally, the enzyme inhibitor is aprotinin, the protease inhibitor is phenylmethylsulfonylfluoride, the non-immune animal protein is bovine serum albumin, and the protease inhibitor is phenylmethylsulfonylfluoride. 0.0 to 0.15 mM of a water-soluble non-interfering salt, such as NaCl, may be desired.

REFERENCES:
patent: 3682776 (1972-08-01), Grundmann et al.
patent: 4681839 (1987-07-01), Swartz

Affiliated with

Also associated with

Rating

Sample collection and transport fluid composition does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Sample collection and transport fluid composition, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sample collection and transport fluid composition will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-33332