Chemistry: analytical and immunological testing – Including sample preparation – Volumetric liquid transfer
Patent
1998-04-16
1999-12-07
Redding, David A.
Chemistry: analytical and immunological testing
Including sample preparation
Volumetric liquid transfer
435 30, 7386411, 7386414, 7386434, G01N 110
Patent
active
059982195
ABSTRACT:
The present invention is directed to methods and apparatus for collecting and pooling the contents of a multiple number of individual sample containers, the apparatus comprising an autoclavable collection bottle capped with a closure-adaptor means having at least one passageway for transfering the fluid contents of the sample containers into the collection bottle. In one embodiment of the invention, the closure-adaptor means comprises a plastic retainer ring for securely holding a flanged cylindrical stopper in which the above-mentioned passageway is formed. Still another aspect of the invention relates to a method of sample testing comprising collecting a pooled sample of a solution or gel, inoculating and/or filtering the pooled sample, and analyzing the inoculated sample or the filter retentate for microbial contamination. For instance, the present method may be used for carrying out either filtered membrane sterility testing or direct transfer preservative efficacy testing of a health care or pharmaceutical product.
REFERENCES:
patent: 4025306 (1977-05-01), Studer
patent: 4829005 (1989-05-01), Friedman et al.
Baritot Richard
Costanzo Stephen
Bausch & Lomb Incorporated
Konkol Chris P.
Magee Mary Anne
Redding David A.
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