Salvinorin derivatives and uses thereof

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

active

07629475

ABSTRACT:
The invention features salvinorin compositions that are selective for kappa opioid receptors; methods of treating mania by using a selective kappa receptor agonist; and methods of treating mood disorders, such as depressive disorders and manic disorders, using salvinorin compositions.

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patent: WO 02/49643 (2002-06-01), None
patent: WO 2005/089745 (2005-09-01), None
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Sheffler et al., “Salvinorin A: The ‘Magic Mint’ Hallucinogen Finds a Molecular Target in the Kappa Opioid Receptor,”Trends Pharm. Sci. 24: 107-109 (2003).
Siebert, Daniel J., “Localization of Salvinorin A and Related Compounds in Glandular Trichomes of the Psychoactive Sage,Salvio divinorum,” Annals of Botany93: 763-771 (2004).
Valdés et al., “Salvinorin C, a New Neoclerodane Diterpene from a Bioactive Fraction of the Hallucinogenic Mexican MintSalvia divinorum,” Org. Lett. 3:3935-3937 (2001).
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