Salts of substituted methylene bisphosphonic acids

Details Salts of substituted methylene bisphosphonic acids Salts of substituted methylene bisphosphonic acids

2007-10-30

2007-10-30

Richter, Johann (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus acids or salts thereof

C562S020000, C562S021000

Reexamination Certificate

active

10725820

ABSTRACT:
A salt of substituted or unsubstituted methylene bisphosphonic acid of formula Iwherein X1and X2are both chlorine or one of X1and X2is hydrogen and one is chlorine and the salt is selected from the group consisting of a C1-16straight or branched primary, secondary or tertiary alkyl amine salt, an aralkyl amine salt, and a basic N-containing heterocycle salt. The salts are used for preparing pharmaceutically relevant compounds.

REFERENCES:
patent: 3251907 (1966-05-01), Roy
patent: 3422021 (1969-01-01), Roy
patent: 4478763 (1984-10-01), McKenna
patent: 4621077 (1986-11-01), Rosini et al.
patent: 4689123 (1987-08-01), Noding
patent: 5237094 (1993-08-01), Lampi et al.
patent: 5376649 (1994-12-01), Pohjala et al.
patent: 6657076 (2003-12-01), Purdie
patent: 1026366 (1966-04-01), None
patent: EP 0200 980 (1986-11-01), None
patent: WO91/03480 (1991-03-01), None
patent: WO 94/18216 (1994-08-01), None
patent: WO 98/45309 (1998-10-01), None
Hutchinson et al., Synthesis of alkylated methylene Bisphosphonate via Organothallium Intermediates, Journal of Organometallic Chemistry 1985, 291 (2), 145-151.
Davission et al., Phosphorylation of Isoprenoid Alcohols, J. Org. Chem., 1986, 51, 4768-4779.
Davission et al., Phosphorylation of Isoprenoid Alcohols, J. Org. Chem., 1986, 51, 4768-4779.
McKenna et al., {Synthesis of e-halogenated methanediphosphonates, Phosphorus and Sulfur and the Related Elements (1988), 37 (1-2), 1-12}.
CA:96:143232 J. Chem. Soc. Chem. Commun. By Blackburn (22) pp. 1188-1190 (1981).
The Merck Index 10thedition Windholz editor p. 4678 (1983).
CA:96:100047 abs of Molekulyarnaya Biologiya (Moscow) by Rozovskaya et al. 15(6) pp. 1205-1223 (1981).
CA:104:149010 abs of J. Organometallic Chem. By Hutchinsom et al 291(2)pp. 145-151 (1985).
CA:106:102549 abs of EP 200980 (Nov. 1986).
CA:101:152243 abs of J. of Chem. Soc. Perkin Trans. 1 by Blackburn et al (5) pp. 119-125 (1984).

Affiliated with

Also associated with

Rating

Salts of substituted methylene bisphosphonic acids does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Salts of substituted methylene bisphosphonic acids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Salts of substituted methylene bisphosphonic acids will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3839337