Salts of phenylpropanolamine with thiazolidine carboxylic acids

Details Salts of phenylpropanolamine with thiazolidine carboxylic acids Salts of phenylpropanolamine with thiazolidine carboxylic acids

1973-11-27

1976-03-30

Gallagher, Richard J.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D27704

Patent

active

039474640

ABSTRACT:
The d,l-phenylpropanolamine racemate is split with optically active thiazolidine-4-carboxylic acids of the formula: ##EQU1## where R.sub.1 R.sub.2 are hydrogen, alkyl of 1 to 8 carbon atoms, cycloalkyl, aryl or alkylene of at least 2 carbon atoms or R.sub.1 and R.sub.2 together form a ring of alkyl or alkylene with 4 to 12 carbon atoms and AC is acyl, especially benzoyl, tosyl, nitrophenylsulfenyl, acetyl or preferably formyl.

REFERENCES:
patent: 2450784 (1948-10-01), Duffin et al.
patent: 3290325 (1966-12-01), Betrand

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