Salts of 5'-methylthio-5'-deoxyadenosine with long-alkyl chain s

Details Salts of 5'-methylthio-5'-deoxyadenosine with long-alkyl chain s Salts of 5'-methylthio-5'-deoxyadenosine with long-alkyl chain s

1985-11-18

1990-11-27

Rollins, John W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 24, C07H 19167

Patent

active

049736787

ABSTRACT:
New salts of 5'-methylthio-5'-deoxyadenosine (MTA) with long-alkyl chain sulphonic acids, which possess central and peripheral vaso-dilatory, platelet antiaggregation, antiinflammatory, analgesic and antipyretic activity.
Said salts are produced by dissolving the sodium salt of the chosen sulphonic acid in distilled water, dissolving the MTA in distilled water to which H.sub.2 SO.sub.4 has been added, reacting together the two solutions to precipitate the MTA sulphonate, and recovering this latter salt with a high degree of purity.

REFERENCES:
patent: 4465672 (1984-08-01), Gennari
Kochetkov et al., Organic Chemistry of Nucleic Acids, Part A, Plenum Press, 1971, pp. 147-150, especially 149-150.

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