Salts of 2-hydroxymalonate platinum complexes

Details Salts of 2-hydroxymalonate platinum complexes Salts of 2-hydroxymalonate platinum complexes

1981-01-22

1982-03-30

Sneed, Helen M. S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07F 1500

Patent

active

043223621

ABSTRACT:
Disclosed are water-soluble salts of the known coordination compounds 2-hydroxymalonato diammine platinum (II), 2-hydroxymalonato (1,2-diaminocyclohexane)platinum (II) and 2-hydroxymalonato (1,1-diaminomethylcyclohexane)platinum (II). The novel sodium and ammonium salts of the present invention possess high water-solubility, thus allowing intravenous dosage forms to be prepared.

REFERENCES:
patent: 4115418 (1978-09-01), Gale et al.
patent: 4140707 (1979-02-01), Cleare et al.

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