Salts of 1,3-bis(.beta.-ethylhexyl)-5-amino-5-methyl-hexahydropy

Details Salts of 1,3-bis(.beta.-ethylhexyl)-5-amino-5-methyl-hexahydropy Salts of 1,3-bis(.beta.-ethylhexyl)-5-amino-5-methyl-hexahydropy

1976-11-03

1979-02-27

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

424 48, 424 54, 424 55, C07D23904, A61K 968

Patent

active

041420500

ABSTRACT:
Novel salts of 1,3-bis-(.beta.-ethylhexyl)-5-amino-5-methyl-hexahydropyrimidine (hexetidine) with substituted benzoic acids and processes of preparing these salts are described. These novel salts have useful bacteriostatic activity and show stability in storage. The invention accordingly comprises compositions containing the novel salts and having bacteriostatic activity. The salts are additionally useful for the purification of hexetidine contained in raw mixtures obtained from the synthesis of this compound.

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Barkley et al., "Antimicrobal Agents Annual", Plenum Press, N.Y. 1961, pp. 507-519.
Higuchi et al., "J. Pharm. Sci.", vol. 53 (6), 1964, pp. 644-651.

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