Salt of proline derivative, solvate thereof, and production...

Details Salt of proline derivative, solvate thereof, and production... Salt of proline derivative, solvate thereof, and production...

2011-08-23

2011-08-23

Bernhardt, Emily (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C514S254020

Reexamination Certificate

active

08003790

ABSTRACT:
The present invention provides 3-{(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl}thiazolidine (compound I) useful as a dipeptidyl peptidase-IV inhibitor, which has superior properties of stability and hygroscopicity, and reproducible crystal structure, and a production method thereof.

REFERENCES:
patent: 5939560 (1999-08-01), Jenkins et al.
patent: 6303661 (2001-10-01), Demuth et al.
patent: 7074794 (2006-07-01), Kitajima et al.
patent: 2004/0106655 (2004-06-01), Kitajima et al.
patent: 2004/0259883 (2004-12-01), Sakashita et al.
patent: 1 308 439 (2003-05-01), None
patent: 1 882 474 (2008-01-01), None
patent: 1 894 567 (2008-03-01), None
patent: WO 97/40832 (1997-11-01), None
patent: WO 98/19998 (1998-05-01), None
patent: WO 01/55105 (2001-08-01), None
patent: WO 02/02560 (2002-01-01), None
patent: WO 02/14271 (2002-02-01), None
patent: WO 02/062764 (2002-08-01), None
“ICH Guideline for Residual Solvents Q3C” Kojima, 1997,available at: http://www.nihs.go.jp/drug/ich—q3c—step4/q3cdrf—9.html, Dec. 12, 2009.
Weber et al.,J. Med. Chem.,47(17): 4135-4141 (2004).
Myerson, Allan S. (Ed.), Handbook of Industrial Crystallization, 2ndEdition, Butterworth-Heinemann 2002, pp. 132-133, 141-148, and 161-167.
International Conference on Harmonisation of Technical Requirements for the Registration of Pharmaceuticals for Human Use, “Impurities: Guideline for Residual Solvents” (Q3C(R3)—Current Step 4 Version) (Nov. 2005).

Affiliated with

Also associated with

Rating

Salt of proline derivative, solvate thereof, and production... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Salt of proline derivative, solvate thereof, and production..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Salt of proline derivative, solvate thereof, and production... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2770830