Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1993-07-09
1997-02-04
Fleisher, Mindy
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
424 934, 4352523, 4352528, A61K 39112, C12N 120, C12N 121
Patent
active
055995373
ABSTRACT:
A vector capable of integrating into the chromosome of Salmonella including a first DNA sequence encoding a heterologous protein, a second DNA sequence encoding a marker, and a third DNA sequence encoding a phoP regulatory region regulated gene product necessary for virulence, the third DNA sequence being mutationally inactivated.
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Mekalanos John J.
Miller, III Samuel I.
Carter Philip W.
Fleisher Mindy
President and Fellows of Harvard College
The General Hospital Corporation
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