Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing
Reexamination Certificate
2005-08-02
2005-08-02
Navarro, Mark (Department: 1645)
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
C424S093200, C424S093400
Reexamination Certificate
active
06923957
ABSTRACT:
Attenuated mutantSalmonellabacteria containing inactivated virulence genes are provided for use in safe, efficacious vaccines.
REFERENCES:
patent: 4877612 (1989-10-01), Berger et al.
patent: 5876931 (1999-03-01), Holden
patent: 109 942 (1991-03-01), None
patent: 180 564 (1991-07-01), None
patent: 231 039 (1992-01-01), None
patent: 0 796 341 (1998-09-01), None
patent: A-2 189 141 (1987-10-01), None
patent: WO 96/17951 (1996-06-01), None
patent: WO 00/14240 (2000-03-01), None
patent: WO 01/47962 (2001-07-01), None
Cardenas et al., Oral Immunization Using Live Attenuated Salmonella spp. as Carriers of Foreign Antigens,Clin Microbiol Rev.5:328-342 (1992).
Chatfield et al., Live Salmonella as Vaccines and Carriers of Foreign Antigenic Determinants,Vaccine7:495-498 (1989).
Clarke et al., Vaccination of Calves with a Diaminopimelic Acid Mutant ofSalmonella typhimurium, Can J Vet Res.51:32-38 (1987).
Curtiss et al., Nonrecombinant and Recombinant Avirulent Salmonella Live Vaccines for Poultry, in Blankenship et al., eds., Colonization control of human bacterial enteropathogens in poultry, Academic Press, New York, pp. 169-198 (1991).
Curtiss et al., Recombinant Avirulent Salmonella for Oral Immunization to Induce Mucosal Immunity to Bacterial Pathogens, in Kohler et al., eds., Vaccines: new concepts and developments. Proceedings of the 10th Int'l Convocation of Immunology, Longman Scientific and Technical, Harlow, Essex, UK, pp. 261-271 (1987).
Curtiss, Attenuated Salmonella Strains as Live Vectors for the Expression of Foreign Antigens, in Woodrow et al., eds., New Generation Vaccines, Marcel Dekker, Inc., New York, pp. 161-188 (1990).
Curtiss et al., Live Oral Avirulent Salmonella Vaccines,Vet. Microbiol.37:397-405 (1993).
Curtiss et al., Recombinant Avirulent Salmonella Vaccine Strains with Stable Maintenance and High Level Expression of Cloned Genes in vivo,Immunol. Invest.18:583-596 (1989).
Donnenberg et al., Construction of an eae Deletion Mutant of EnteropathogenicEscherichia coliby Using a Positive-Selection Suicide Vector,Infect. and Immun.59:4310-4317 (1991).
Dunyak et al., Identification of Salmonella Pathogenicity Island 2 (SPI2) Genes inSalmonella choleraesuisSignature-Tagged Mutagenesis, 97th General Meeting of the American Society for Microbiology, May 4-8, 1997, Miami Beach, Florida, American Society for Microbiology, Washington, D.C. (1997), p. 76. (Abstract).
Galan et al., Cloning and Characterization of the asd gene ofSalmonella typhimurium:Use in Stable Maintenance of Recombinant Plasmids in Salmonella Vaccine Strains,Gene94:29-35 (1990).
GenBank Accession No. AJ224892,Salmonella typhimuriumssaE, sseA, sseB, sscA, sseC, sseD, sseE, sscB, sseF, sseG, ssaG, ssaH, ssaI genes and partial ssaD, ssaJ genes, Hensel, M., 1998.
GenBank Accession No. U51927,Salmonella typhimuriumSpiR and SpiB genes, partial cds, and SpiC and SpiA genes. complete cds, Groisman, E., 1996.
GenBank Accession No. X99944,Salmonella typhimuriumssaQ, ssaR, ssaS, ssaT and ssaU genes, Hensel, M., 1997.
GenBank Accession No. Y09357,S. typhimuriumssaJ, ssaK, ssaL, ssaM, ssaV, ssaN, ssaO, ssaP, ssaQ genes, Hensel, M. et al., 1997.
GenBank Accession No. Z95891,S. typhimuriumssrA and ssrB genes, Hensel, M., 1998.
Germanier et al., Immunity in Experimental Salmonellosis, II. Basis for the Avirulence and Protective Capacity of gal E Mutants,Infect. and Immun.4:663-673 (1971).
Hensel et al., Analysis of the Boundaries of Salmonella Pathogenicity Island 2 and the Corresponding Chromosomal Region ofEscherichia coliK-12,J. Bacteriol.179:1105-1111 (1997).
Hensel et al., Functional analysis of ssaJ and ssaK/U operon, 13 genes encoding components of the type III secretion apparatus of Salmonella Pathogenicity Island 2,Molec. Microbiol.24:155-167 (1997).
Hohmann et al., Intestinal and Serum Antibody Responses in Mice After Oral Immunization with Salmonella,Escherichia coli,andSalmonella-Escherichia coliHybrid Strains,Infect. and Immun.25:27-33 (1979).
Hoiseth et al., Aromatic-dependentSalmonella typhimuriumAre Non-virulent and Effective as Live Vaccines,Nature291:238-239 (1981).
Hone et al., Construction of Defined galE Mutants of Salmonella for Use as Vaccines,J. Infect. Dis.156:167-174 (1987).
Horton et al., Gene Splicing by Overlap Extension: Tailor-Made Genes Using the Polymerase Chain Reaction,Biotechniques8:528-535 (1990).
Kennedy et al., Characterization and Protective Properties of Attenuated Mutants ofSalmonella dublin,97th General Meeting of the American Society for Microbiology, B-287:78 (1997.).
Letellier et al., Assessment of various treatments to reduce carriage of Salmonella in swine,The Canadian Journal of Veterinary Research64:27-31 (2000).
Levine et al., Safety, Infectivity, Immunogenicity, and In Vivo Stability of Two Attenuated Auxotrophic Mutant Strains ofSalmonella typhi,541Ty and 543Ty, as Live Oral Vaccines in Humans,J. Clin. Invest.79:888-902 (1987).
Lindberg et al., Antibody Response and Protection against Challenge in Mice Vaccinated Intraperitoneally with a Live aroA O4-O9 HybridSalmonella dublinStrain,Infect. and Immun.61:1211-1221 (1993).
Linde et al., Stable Salmonella Live Vaccine Strains with Two or More Attenuating Mutations and Any Desired Level of Attenuation,Vaccine8:278-282 (1990).
McFarland et al., Effect of Different Purine Auxotrophic Mutations on Mouse-Virulence of a Vi-Positive Strain ofSalmonella dublinand Two Strains ofSalmonella typhimurium, Microb. Pathogen.3:129-141 (1987).
Mills et al., A 40kb Chromosomal Fragment EncodingSalmonella typhimuriumInvasion Genes Is Absent from the Corresponding Region of theEscherichia coliK-12 Chromosome,Mol. Microbiol.5:749-759 (1995).
Nnalue et al., Some galE Mutants ofSalmonella choleraesuisRetain Virulence,Infect. and Immun.54:635-640 (1986).
Nnalue et al., Tests of the Virulence and Live-Vaccine Efficacy of Auxotrophic and galE Derivatives ofSalmonella choleraesuis, Infect. and Immun.55:955-962 (1987).
O'Callaghan et al., Characterization of Aromatic- and Purine-DependentSalmonella typhimurium:Attenuation, Persistence, and Ability to Induce Protective Immunity in BALB/c Mice,Infect. and Immun.56: 419-423 (1988).
O'Callaghan et al., Immune Responses in BALB/c Mice Following Immunization with Aromatic Compound or Purine-DependentSalmonella typhimuriumStrains,Immunology69:184-189 (1990).
Ochman et al., Identification of a pathogenicity island required for Salmonella survival in host cells,Proc. Natl. Acad. Sci.(USA) 93:7800-7804 (1996).
Reyrat et al., Counterselectable Markers: Untapped Tools for Bacterial Genetics and Pathogenesis,Infect. and Immun.66:4011-4017 (1998).
Robertsson et al.,Salmonella typhimuriumInfection in Calves: Protection and Survival of Virulent Challenge Bacteria After Immunization with Live or Inactivated Vaccines,Infect. and Immun.41:742-750 (1983).
Shea et al., Identification of a virulence locus encoding a second type III secretion system inSalmonella typhimurium, Proc. Natl. Acad. Sci.(USA) 93:2593-2597 (1996).
Smith et al., Vaccination of Calves with Orally Administered Aromatic-DependentSalmonella dublin, Am. J. Vet. Res.54:1249-1255 (1993).
Smith et al., Aromatic-dependentSalmonella typhimuriumas Modified Live Vaccines for Calves,Am. J. Vet. Res.45:59-66 (1984).
Smith et al., Aromatic-dependentSalmonella dublinas a Parenteral Modified Live Vaccine for Calves,Am. J. Vet. Res.45:2231-2235 (1984).
Tacket et al., Comparison of the Safety and Immunogenicity of ΔaroC ΔaroD and Δcya ΔcrpSalmonella typhiStrains in Adult Volunteers,Infect. and Immun.60:536-541 (1992).
Zhang et al., An RNA Helicase, RHIV-1, Induced by Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is Mapped on Porcine Chromosome 10q13,Microb. Pathogen.28:267-278(2000)..
Kennedy Michael J.
Lowery David E.
Navarro Mark
Pharmacia & Upjohn Company
Pharmacia & Upjohn Company
Wootton Thomas A.
LandOfFree
Salmonella vaccine materials and methods does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Salmonella vaccine materials and methods, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Salmonella vaccine materials and methods will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3444622