Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Reexamination Certificate
2005-03-01
2005-03-01
Minnifield, Nita (Department: 1645)
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
C435S004000, C435S006120, C435S030000, C435S032000, C435S038000, C435S252100, C435S243000, C536S022100, C536S023100, C536S023700, C424S234100, C424S258100
Reexamination Certificate
active
06861247
ABSTRACT:
Substantially pure Salmonella secreted proteins (Ssp), the sercetion of which is dependent upon the expession of PrgH; methods of diagnosing Salmonella infection; and live attenuated vaccine strains in which Ssp secretion is decreased.
REFERENCES:
patent: 4603152 (1986-07-01), Laurin et al.
patent: 5972899 (1999-10-01), Zychlinsky et al.
patent: WO 9011687 (1990-10-01), None
patent: WO 9217785 (1992-10-01), None
patent: WO 9502048 (1995-01-01), None
Boehringer Mannheim Biochemicals (1991 Catalog p. 557).*
Stratagene (1991 Product Catalog, p. 66).*
Gibco BRL (Catalogue & Reference Guide 1992, p. 292).*
Promega (1993/1994 Catalog, pp. 90-91).*
New England BioLabs (Catalog 1986/1987, pp. 60-62).*
Collazo et al 1995, Molecular Microbiology, 15(1), 25-38.*
Harris et al. J. of he Am Society of Nephrology 6:1125-33, 1995.*
Anh et al. Nature Genetics 3(4): 283-91, 1993.*
Cawthon et al. Genomics 9(3): 446-60, 1991.*
Hermant et al. “Functional conservation of the Salmonella and Shigella effectors of entry into epithelial cells”Molecular Microbiology17,4:781-789 (1995).
Kangia et al. “Homologs of the Shigell IpaB and IpaC Invasins Are Require forSalmonella typhimuriumEntry into Cultured Epithelial Cells”Journal of Bateriology117,14:3965-3971 (1995).
Pegues et al. “PhoP/PhoQ transcriptional repression ofSalmonella typhimuriuminvasion gene: evidence for a role in protein secretion”Molecular Microbiology17,1:169-181 (1995).
EMBL Accession No. U25631, Sep. 6, 1995, Kaniga et al.
EMBL Acession No. x82670, Oct. 4, 1995, Hermant et al.
Allaoui et al., “MxiD, an outer membrane protein necessary for the secretion of theShigella flexneriIpa invasins” Molecular Microbiology 7:59-68 (1993).
Allaoui et al., MxiJ, a Lipoprotein Involved in Secretion of Shigella Ipa Invasins, Is Homolgous to YscJ, a Secretion Factor of the Yersinia Yop Proteins Journal of Bacteriology, 174:7661-7669 (1992).
Andrews et al., “Two Novel Virulence Loci, mxiA an mxiB, inShigella flexneri2a Facilitate Excretion of Invasion Plasmid Antigens” Infection and Immunity, 59:1997-2005 (1991).
Andrews et al., “mxiA ofShigella flexneri2a, Which Facilitates Export of Invasion Plasmid Antigens, Encodes a Homolog of the Low-Calcium-Response Protein, LcrD, ofYersinia pestis” Infect. & Immun., 60:3287-3295 (92).
Babinet et al., “Specific Expression of Hepatitis B Surface Antigen (HBsAg) in Transgenic Mice” Science, 230:1160-1163 (1985).
Baudry et al., “Localization of Plasmid Loci Necessary for the Entry ofShigella flexneriinto HeLa Cells, and Characterization of One Locus Encoding Four Immunogenic Polypeptides” Journal Gen. Microbiology 133: 3403-3413 (1987).
Behlau et al., “A PhoP-Repressed Gene PromotesSalmonella typhimuriumInvasion of Epithelial Cell” J. Bacteriol. 175:4475-4484 (1993).
Collazo et al., “Functional analysis of theSalmonella typhimuriuminvasion gene invL and invJ and identication of a target of the protein secretion apparatus encoded in the inv Locus” Mol. Micro. 15:25-38,(1995).
Feng et al., “Progressive Sequence Alignment as a Prerequisite to Correct Phylogenetic Trees” J. Mol. Evol. 25:351-360 (1987).
Groisman et al., Cognate gene clusters govern invasion of host epithelial cells bySalmonella typhimriumandShigella flexneri, The Embo Journal, 3779-3787 (1993).
Hantman et al., “Defective Extracellular Protein Secretion bySalmonella typhimuriumMutants Impaired in Induction of Eucaryotic Cell Membrane Ruffling and Macrophinocytosis” American society for Microbiology (May 21-25, 1995) pp. 183-185.
Hermant et al., “Functional conservation of the Salmonella and Shigella effectors of entry into epithelial cells,” Molecular Microbiology, 17:781-789, (1995).
Higgins et al., “Fast and sensitive multiple sequence alignments on a microcomputer” Cabios Communications, 5:151-153 (1989).
Hueck et al., “Salmonella typhimuriumsecreted invasion determinants are homologous to Shigella Ipa proteins,” Molecular Microbiology, 18:479-490, (1995).
Kaniga et al., “Homologs of the Shigella IpaB and IpaC Invasins Are Required forSalmonella typhimuriumEntry into Cultured Epithelial Cells”, Journal of Bacteriology, 177:3965-3971, (1995).
Menard et al., “The secretion of theShigella flexneriIpa invasins is activated by epithelial cells and controlled by IpaB an IpaD” The Embo Journal 5293-5302 (1994).
Miller et al., “A two-component regulatory system (phoP phoQ) controlsSalmonella typhimuriumvirulence” Proc. Natl. Acad. Sci. USA, 86:5054-5085, (1989).
Miller et al., “Salmonella Vaccines with Mutations in the phoP Virulence Regulon” Res. Microbiol. 141:817-821, (1990).
Miller et al., “Constitutive Expression of the PhoP Regulon Attenuates Salmonella Virulence and Survival within Macrophages” J. Bacteriol., 172:2485-2490, (1990).
Mills et al., “A 40 kb chromosomal fragment encodingSalmonella typhimuriuminvasion genes is absent from the corresonding region of theEschericia coliK-12 chromosome” Molecular Microbiology 15:749-759 (1995).
Paradee et al., “Assay of β-Galactosidase” Journal of Bacteriology, 174:352-355 Experiment 48 (1992).
Pegues et al., “PhoP/PhoQ transcriptional repression ofSalmonella typhimuriuminvasion genes: evidence for a role in protein secretion” Molecular Microbiology, 17:169-181 (1995).
Pulkkinen et al., “ASalmonella typhimuriumVirulence Protein Is Similar to aYersinia enterocoliticaInvasion Protein and a Bacteriophage Lambda Outer Membrane Protein”Journal of Bacteriology, 173:86-93 (1991).
Sasakawa et al., “Functional organization and nucleotide sequence of virulence Region-2 on the large virulence plasmid inShigella flexneri 2a” Molecular Microbiology 3:1191-1201 (1989).
Sory et al., “Translocation of a hybrid YopE-adenylate cyclase fromYersinia enterocoliticainto HeLa cells” Molecular Microbiology, 14:583-594 (1994).
Venkatesan et al., “Characterization of invasion plasmid antigen genes (ipaBDC) fromShigella flexneri” Proc. Natl. Acad. Sci. 85:9317-9321 (1988).
Supplementary European Search Report (EP 92 90 4089).
Baskar Padma
Fish & Richardson P.C.
Minnifield Nita
The General Hospital Corporation
LandOfFree
Salmonella secreted proteins and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Salmonella secreted proteins and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Salmonella secreted proteins and uses thereof will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3416586