Saliva test for feline leukemia virus

Details Saliva test for feline leukemia virus Saliva test for feline leukemia virus

1988-03-17

1990-05-08

Nucker, Christine M.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

422 57, 422 58, 422 61, 422 69, 435 7, 435805, 435810, 436518, 436527, 436531, 436548, 436808, 436810, 436811, G01N 33569, G01N 33577

Patent

active

049237985

ABSTRACT:
An immunoassay method and apparatus for diagnosing FeLV-induced, persistent viremia is provided comprising combining a feline saliva sample conveniently obtained with a specially designed probe, with anti-p27 antibodies and detecting complex formation as indicative of the viremia. Preferably, the antibodies are bound to the probe for complex formation.

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patent: 4379839 (1980-02-01), Spiegelman
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patent: 4637978 (1987-01-01), Dappen
patent: 4663277 (1987-05-01), Wang
patent: 4689309 (1987-08-01), Jones
Francis et al, Leukemia Research (1979), 3:435-441 entitled "Feline Leukemia Virus Infections: The Significance of Chronic Viremia".
Francis et al., J. Clin. Pathol. (1979), 32:514-515 entitled "A simple method for quantitating salivary levels of virus using calcium alginate swabs".
Francis et al, J. Clin. Microbiol. (1979), 9:154-156 entitled "Feline Leukemia Virus: Survival Under Home and Laboratory Conditions".
Francis et al., Nature (1977), 269:252-254 entitled "Excretion of feline leukemia virus by naturally infected pet cats".
Hoover et al., Cancer Research (1977), 37:3707-3710 entitled "Relationship between Feline Leukemia Virus Antigen Expression and Viral Infecticity in Blood, Bone Marrow, and Saliva of Cats".
W. P. Collins, John Wiley & Sons (1985), "Alternative Immunoassays", p. 235, Hiramatsu, Clin. Chim. Acta (1981), 117:239-249 entitled "Direct assay of cortisol in human saliva by solid phase radioimmunoassay and its clinical applications".
Lutz et al., J. Clin. Microbiol. (1987), 25:827-831 entitled "Detection of Feline Leukemia Virus Infection in Saliva".

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