Salicyloyl-carnitine and process for its production

Details Salicyloyl-carnitine and process for its production Salicyloyl-carnitine and process for its production

1992-02-11

1993-07-13

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 71, C07C 6988

Patent

active

052275140

ABSTRACT:
Salicylic acid esters of carnitine are distinguished relative to acetylsalicylic acid by high water solubility, low toxicity and good stomach tolerance. The compounds are obtainable in three stages from carnitine hydrochloride and o-methoxybenzoyl chloride.

REFERENCES:
patent: 4271310 (1981-06-01), Watanabe
patent: 4336400 (1982-06-01), Minatoya et al.
Okabe et al., Japan. J. Pharmacol., 24, (1974), pp. 363 to 371.
Chaumontet et al., Arzneimittelforschung [Pharmaceutical Agent Research], 28, (1978), pp. 2119 to 2121.

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