SAF polypeptide gene coding therefor, and SAF promoter

Details SAF polypeptide gene coding therefor, and SAF promoter SAF polypeptide gene coding therefor, and SAF promoter

1989-05-19

1992-06-16

Peet, Richard C.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

536 27, 435 6, 435 691, 435 712, 435 91, 435169, 4351721, 4351723, 4352523, 43525235, 4353201, 935 6, 935 9, 935 22, 935 29, 935 59, 935 60, 935 61, 935 66, 935 72, 935 75, C07K 1300, C07K 1500, C12N 1531

Patent

active

051225956

ABSTRACT:
The cloning and characterization of a newly isolated gene, referred to as saf (secondary metabolism activation factor) is disclosed. This gene encodes a new amino acid polypeptide, referred to as the SAF polypeptide, which directly or indirectly modulates the expression of extracellular enzymes in Steptomyces. DNA units or fragments which encode the SAF polypeptide are also disclosed, as are vectors containing said DNA, host organisms transformed with such vectors, and processes for preparing extracellular enzymes or heterologous polypeptides by culturing such host organisms.

REFERENCES:
Horinouchi et al., 1983, J. Bacteriol., vol. 155(31):1238-1248.

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