Saccharin derivatives useful as proteolytic enzyme inhibitors an

Details Saccharin derivatives useful as proteolytic enzyme inhibitors an Saccharin derivatives useful as proteolytic enzyme inhibitors an

1997-02-20

1999-02-23

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514254, 514321, 514373, 546198, 544135, 544368, 548210, A61K 31535, C07D27506

Patent

active

058744320

ABSTRACT:
Novel 2-substituted saccharins which inhibit the enzymatic activity of proteolytic enzymes, are useful in the treatment of degenerative diseases and have the formula ##STR1## wherein: L is --O--, --S--, --SO-- or --SO.sub.2 --;

REFERENCES:
patent: 3002884 (1961-10-01), Lo
patent: 3284450 (1966-11-01), Kraaijeveld et al.
patent: 3314960 (1967-04-01), Freed et al.
patent: 4195023 (1980-03-01), Mulvey et al.
patent: 4263393 (1981-04-01), Chen
patent: 4276298 (1981-06-01), Jones et al.
patent: 4350752 (1982-09-01), Reczek et al.
patent: 4363865 (1982-12-01), Reczek et al.
patent: 4410618 (1983-10-01), Vanmeter et al.
patent: 4547371 (1985-10-01), Doherty et al.
patent: 4623645 (1986-11-01), Doherty et al.
patent: 4659855 (1987-04-01), Powers
Cha, Biochem. Pharmacol., 24,2177-2185 (1975).
Powers, et al. Biochem., 24, 2048-2058 (1985).
Svoboda et al., Coll. Czech. Chem. Commun., 51, 1133-1139 (1986).
Teshima et al., J. Biol. Chem. 257(9), 5085-5091 (1982).
Amal et al., Chemical Abstract 68:2688h (1967).
Yoon et al., Chemical Abstract 107:77681h (1987).
Svoboda et al., Chemical Abstracts 110:38982Z (1989).
Bors et al., Chemical Abstracts 80:37097q (1973).

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