s-Triazolo(3,4-I)purine derivatives

Details s-Triazolo(3,4-I)purine derivatives s-Triazolo(3,4-I)purine derivatives

1991-08-23

1992-12-22

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544251, A61K 31505, C07D23970

Patent

active

051734923

ABSTRACT:
There are disclosed s-triazolo[3,4-i]purine derivatives represented by formula: ##STR1## wherein Y-Z represents ##STR2## R.sub.4 represents hydrogen, alkyl, substituted or unsubstituted aromatic heterocyclic group or substituted or unsubstituted aryl; and X.sup.2 represents oxygen, sulfur or NH; each of R.sup.1 and R.sup.2 independently represents hydrogen, alkyl, cycloalkyl, aralkyl or substituted or unsubstituted aryl; R.sup.3 represents alkyl, cycloalkyl, aralkyl or substituted or unsubstituted aryl; X.sup.1 represents oxygen or sulfur; and represents a single bond or a double bond or pharmaceutically acceptable salts thereof.

REFERENCES:
Brown et al, Aust. J. Chem. 35, 1263-7, 1982.
Carroll et al; J. Org. Chem. 30, 3601-3603 1965.
Brown et al., 3 Alkylthio-s-triazolo[3,4-i]purines and 9-Alkylbis-s-triazolo [3,4-b:3,', 4'-i]purines, Aust. J. Chem., 1982, 1263-7.

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