S.sub.3 N chelating compounds

Details S.sub.3 N chelating compounds S.sub.3 N chelating compounds

1990-09-28

1993-10-12

Stoll, Robert L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Radioactive metal containing

534 10, C07F 500

Patent

active

052527212

ABSTRACT:
Novel chelating compounds and the corresponding radionuclide metal chelates are useful for radiolabeling proteins such as antibodies with radionuclide metals such as .sup.99m Tc, .sup.186 Re, and .sup.188 Re. The chelating compounds are of the following formulas: ##STR1## wherein each R is a protecting group;

REFERENCES:
patent: 2810753 (1957-10-01), Bersworth
patent: 4571430 (1986-02-01), Byrne et al.
patent: 4789736 (1988-12-01), Canning et al.
patent: 4839467 (1989-06-01), Deutsch
patent: 4849511 (1989-07-01), Verbruggen
patent: 4861869 (1989-08-01), Nicolotti et al.
patent: 4883862 (1989-11-01), Chervu et al.
patent: 4897255 (1990-01-01), Fritzberg et al.
patent: 4963682 (1990-10-01), Bodor
patent: 4963688 (1990-10-01), Bodor
patent: 4965392 (1990-10-01), Fritzberg et al.
patent: 4988496 (1991-01-01), Srinivasan et al.
Lever et al., Tetrahedron Letters, vol. 29, No. 26, pp. 3219-3222, 1988 (printed in Great Britain), "Synthesis of a novel bifunctional chelate designed for labeling proteins with technetium-99m" Mastrostamatis et al., Eur. J. Nucl. Med., Suppl. to vol. 16, 1990.
Abstract No. 428, "Tripodal N,S.sub.3 -donor ligands as a new backbone for reduced technetium".
Corbin et al., Inorganica Chimica Acta, 90 (1984), pp. 41-51, "Preparation and properties of tripodal and linear tetradentate N,S-donor ligands and their complexes containing the MoO.sub.2.sup.2+ core".

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