S-modified adenosyl-1,8-diamino-3-thiooctane derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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514261, 514266, A61K 3152, C07D47334

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active

048032727

ABSTRACT:
S-Modified Adenosyl-1,8-Diamino-3-Thiooctane derivatives which are useful as interferon potentiators and polyamine biosynthesis inhibitors are disclosed.

REFERENCES:
patent: 4221794 (1980-09-01), Simon
patent: 4230708 (1980-10-01), De Clerq
patent: 4362729 (1982-12-01), Vince
patent: 4376116 (1983-03-01), Coward et al.
patent: 4543255 (1985-09-01), Shealy
patent: 4649140 (1987-03-01), Schaeffer
Beauchamp, (1985), J. Med. Chem., 28, pp. 982-987.
Sunkara et al., Science, 219:851 (1983).

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