(S)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D207277

Patent

active

049436392

ABSTRACT:
(S)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide, its preparation and pharmaceutical compositions containing the same. It can be prepared either by reacting (S)-alpha-ethyl-2-oxo-1-pyrrolidineacetic acid successively with an alkyl haloformate and with ammonia, or, by cyclizing an (S)-2-amino-butanamide of the formula X--CH.sub.2 CH.sub.2 --Y--NHCH(C.sub.2 H.sub.5)CONH.sub.2 wherein Y is a --CH.sub.2 -- radical when X represents a ZOOC-- radical and Y is a --CO-- radical when X represents a HalCH.sub.2 -- radical, Z being a C.sub.1 -C.sub.4 alkyl radical and Hal a halogen atom.
This laevorotatory enantiomer has been found to have significantly higher protective activity against hypoxia and ischemia than the corresponding racemate.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

(S)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with (S)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and (S)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1268472

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.