S-adenosyl methionine decarboxylase inhibitors

Details S-adenosyl methionine decarboxylase inhibitors S-adenosyl methionine decarboxylase inhibitors

1992-06-09

1995-05-16

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 2731, A61K 3170, C07H 19167

Patent

active

054160766

ABSTRACT:
The adenosine derivatives represented by the following formula: ##STR1## and the pharmaceutically acceptable salts thereof wherein R is H or C.sub.1 -C.sub.7 alkyl,

REFERENCES:
patent: 4134918 (1979-01-01), Bey et al.
patent: 4794174 (1988-12-01), Secrist, III
Davis et al. (1983) Aust. J. Chem., vol. 36, pp. 1623-1627.
Casara et al. (1984) Tetrahedron Letters, vol. 25, No. 18, pp. 1891-1894.
Metcalf et al. (1978) J. Am. Chem. Soc., vol. 100, No. 8, 2551-2553.
Pugh et al. (1982) Biochemistry, vol. 21, 1535-1541.
Minnick et al. (1988) J. Org. Chem., vol. 53, 4952-4561.
Reich et al. (1990) J. Biol. Chem., vol. 265, No. 15, 8966-8970.
Anton et al. (1987) Biochemistry, vol. 26, 6444-6447.
Chang et al, (1976) J. Med. Chem. vol. 14, No. 5, pp. 684-691.
Santi et al. (1987) Biochemistry, vol. 26, 8599-8606.
Casara et al. (1989) J. Am. Chem. Soc., vol. 111, No. 25, pp. 9111-9113.
Bijonti et al, (1990) Antimicro. Agents Chemotherapy, vol. 34, No. 8, 1485-1490.
Pegg, Anthony E., et al., Biochemistry 27, pp. 1408-1415, (1988).
Chemical Abstracts 100:103834, M. Davis, et al.
Kolb, Michael, et al., J. Med. Chem. 25, pp. 550-556 (1982).
Pankaskie, Marvin, et al., J. Med. Chem. 23, pp. 121-127 (1980).
J. S. Secrist, III, Nucleosides & Nucleotides 6, No. 1-2, pp. 73-83 (1987).

Affiliated with

Also associated with

Rating

S-adenosyl methionine decarboxylase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with S-adenosyl methionine decarboxylase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and S-adenosyl methionine decarboxylase inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-637768