S-[2-phenyl (alkyl) carbamoyl]-phenylselenylmercapto derivatives

Details S-[2-phenyl (alkyl) carbamoyl]-phenylselenylmercapto derivatives S-[2-phenyl (alkyl) carbamoyl]-phenylselenylmercapto derivatives

1985-11-25

1988-03-08

Moyer, Donald B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

260550, 514347, 514357, 514522, 514533, 514535, 514539, 514562, 514618, 546330, 546335, 558415, 560 9, 560 16, 560 18, 562426, 562432, C07C16300, A61K 3144, A61K 31165

Patent

active

047300531

ABSTRACT:
The present invention is related to new S-(Carbamoyl-phenylselenyl) derivatives of mercaptanes of the general formula (I) ##STR1## and to a process for the treatment of diseases caused by cell injury due to the increased formation of active oxygen metabolites.

REFERENCES:
patent: 4352799 (1982-10-01), Renson et al.
patent: 4418069 (1983-11-01), Welter et al.
patent: 4618669 (1986-10-01), Dereu et al.
Fundamental and Applied Toxicology (3) 9-10 (1983), pp. 431-436, Reddy et al.
Agents and Actions, Supp. 7, pp. 214-219, Bragt et al.
Methods of Enzymology, vol. 77, pp. 325-333 (1981), Wendel.
Free Radicals in Biology, vol. V, pp. 223-254, Leopold Flohe.

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