Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-01-22
1993-11-02
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546 75, C07D22118, A61K 3147
Patent
active
052583848
ABSTRACT:
S-11-hydroxy-10-methylaporphine and its biologically active salt forms are used as 5-HT.sub.1A inhibitors. Since these compounds function as 5-HT.sub.1A they can be used as an antidote for effects of cocaine and as appetite suppressants.
S-11 Hydroxy-10-Methylaporphine has the formula: ##STR1##
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Duhault et al "Brain Serotonergic System and Anorectic Drugs" Central Mechanisms of Anorectic Drugs, Raven Press, New York (1978), pp. 205-215.
Bhatnagar Ranbir K.
Cannon Joseph G.
Long John P.
Moe Scott T.
British Technology Group Limited
Datlow Philip I.
Shah Mukund J.
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