(S)-1-[10-chloro-6,7-dihydro-4-oxo-3-phenyl-4H-benzo[a]quino-liz

Details (S)-1-[10-chloro-6,7-dihydro-4-oxo-3-phenyl-4H-benzo[a]quino-liz (S)-1-[10-chloro-6,7-dihydro-4-oxo-3-phenyl-4H-benzo[a]quino-liz

1992-01-06

1994-01-25

Michl, Paul R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424434, 424436, 424451, 424456, 424459, 424463, 424464, 424474, 424DIG15, C07D45506, A61F 1302, A61K 948, A61K 928

Patent

active

052817113

ABSTRACT:
The compound (S)-1-[(10-chloro-6,7-dihydro-4-oxo-3-phenyl-4H-benzo[a]quino-lizin-1-yl)c arbonyl]-3-ethoxypyrrolidine of the formula ##STR1## which has valuable pharmacological properties, is described. In particular, the compound of formula I has a non-sedating, hypnotic, that is, sleep-promoting, activity and can accordingly be used for the treatment of sleep disorders.

REFERENCES:
patent: 4889848 (1989-12-01), Fischer et al.
"Tricyclic Pyridine Derivatives With High Affinity to the Central Benzodiazepine Receptor", Fisher et al, Helv. Chim. Acta, 73(4), 763-81, 1990.

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