RXR selective ligands

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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Details

562405, 549 79, 546342, C07C 6116, C07C 6300, C07D33324, C07D21170

Patent

active

059861312

ABSTRACT:
Novel nonatetraenoic acid derivatives which selectively bind to retinoic acid X-receptors (RXR) and which have anti-acne acitvity and which potentiate the activity of retinoids having RAR.alpha. activity are disclosed.

REFERENCES:
patent: 5514672 (1996-05-01), Bazzano
Paust et al, "Agent containing an all-E- or 13-Z-7,8-dehydroretinoic acid", Chem. Abs.No.93:155854, 1980.

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