Measuring and testing – Gas content of a liquid or a solid – By vibration
Reexamination Certificate
2004-04-14
2009-06-09
Williams, Hezron (Department: 2856)
Measuring and testing
Gas content of a liquid or a solid
By vibration
C073S024030, C073S024060, C073S031060, C073S061750, C073S061710, C073S053010, C073S579000
Reexamination Certificate
active
07543476
ABSTRACT:
An apparatus for separating an analyte from a mixture or for detecting an analyte or for determining the affinity, or a property related to affinity, between binding partners includes: a) a surface having the analyte or one of the binding partners immobilized thereon, in use; b) a transducer for oscillating the surface; c) a controller connected to the transducer for varying the amplitude and/or frequency of the oscillation to cause a dissociation event; and, d) an analyzer connected to the transducer for detecting an oscillation of the transducer due to the dissociation event. The controller includes an oscillator connected in a resonant circuit with the transducer such that the transducer oscillates at two frequencies simultaneously, one of these causing the transducer to oscillate the surface and the other being supplied as an output to the analyzer.
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F. N. Dultsev et al., “Direct and Quantitative Detection of Bacteriophage by ‘Hearing’ Surface Detachment Using a Quartz Crystal Microbalance”, Analytical Chemistry, American Chemical Society, vol. 73, No. 16, Aug. 15, 2001, pp. 3935-3939, XP-001089327.
Akubio Limited
Blank Rome LLP
Miller Rose M
Williams Hezron
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