Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1995-05-10
1999-09-21
Jagannathan, Vasu S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 8, 514 12, 530350, 530395, A61K 3818, C07K 14475
Patent
active
059554207
ABSTRACT:
An activator of the Rse receptor protein tyrosine kinase has been identified which is encoded by growth arrest-specific gene 6 (gas6). Accordingly, the present invention provides a method of activating the Rse receptor by exposing a cell comprising the Rse receptor to exogenous gas6 polypeptide. Moreover, the present invention is directed to a method for enhancing the survival, proliferation or differentiation of a cell comprising a Rse receptor by exposing the cell to exogenous gas6 polypeptide. The types of cells which can be treated according to the method include glial cells such as Schwann cells.
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Chen Jian
Godowski Paul J.
Hammonds R. Glenn
Li Rong-hao
Mark Melanie R.
Genentech Inc.
Jagannathan Vasu S.
Lee Wendy
Saoud Christine
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