Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Nucleoproteins – e.g. – chromatin – chromosomal proteins,...
Patent
1995-09-14
1997-08-19
Scheiner, Toni R.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Nucleoproteins, e.g., chromatin, chromosomal proteins,...
530350, 5303879, 5303881, 5303891, A61K 3816, C07K 100, C07K 1400, C07K 1700
Patent
active
056590164
ABSTRACT:
The 5-terminal partially nucleotide sequence of each clone of a human fetal lung tissue cDNA library was determined. A clone having a novel sequence including a sequence homologous to that of the transcriptional control protein of a yeast was selected from among the above clones and its whole nucleotide structure was determined. It was confirmed that the protein encoded by the gene of the clone was a novel human transcriptional control protein (RPDL protein). Further, an expression vector for expressing the protein and a transformant obtained by transforming with such an expression vector can also be prepared.
REFERENCES:
Grundy et al Mol. Microbiol. vol. 10 p. 259 1993.
Mol. Cell. Biol., vol. 11, No. 12, Dec. 1991, pp. 6317-6327, Vidal. M. & Gaber, R.F. `RPD3 encodes a second factor . . . `.
Genomics, vol. 24, No. 2, 15 Nov. 1994, pp. 276-279, Sudo, K. et al. `2058 expressed sequence tags . . . ` & DDBJ database entry HSL13977, accession No. D31480.
EMBL database entry Xlab 21, accession No. X78454, submitted 25 Mar. 1994; Ladomery, M.R. et al, "yeast RPD3 homologue from X. laevis".
Scientific American, vol. 260, Jun. 1989, pp. 40-47, Holliday, R. `A different kind of inheritance`.
Furukawa Yoichi
Nakamura Yusuke
Cancer Institute
Eisai Co. Ltd.
Huff Sheela J.
Scheiner Toni R.
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