Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Patent
1997-02-19
1998-06-30
Degen, Nancy
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
4352351, 4353201, A61K 3915, C12N 700, C12N 701, C12N 1563
Patent
active
057730091
ABSTRACT:
Provided is an isolated rotavirus of the strain G9P11, an isolated nucleic acid encoding the rotavirus of strain G9P11 and a purified antigen specific for the rotavirus. An isolated nucleic acid encoding the antigen of the rotavirus is also provided, as is an isolated nucleic acid that selectively hybridizes under high stringency conditions with the nucleic acid encoding te virus. A purified antibody which selectively binds the virus of strain G9P11 is provided. The G9P11 rotavirus in a pharmaceutically acceptable carrier for administration in an immunization protocol is provided. Also provided is an isolated rotavirus of strain G9P11, wherein the G9 gene is substituted. Further provided is an isolated rotavirus of strain G9P11, wherein the P11 gene is substituted.
REFERENCES:
patent: 5474773 (1995-12-01), Ward
Bhan et al. J. Infect. Diseases 168:282-287, 1993.
Gentsch et al. Virol. 194:424-430, 1993.
Das et al. Virol. 197:99-107, 1993.
Das et al. Virol. 194(1):374-379, 1993.
Gentsch et al. J. Clin. Microbiol. 30(6):1365-1373, 1992.
Bhan et al. Plediatr. Infect. Dis. J. 7(5):320-323, 1988.
Jayashree et al. J. Infect. Dis. 158(5):1117-1120, 1988.
Glass et al. Virol. 141:292-298, 1985.
Hardy et al, Virology, 1992, vol. 191:pp. 291-300.
Bhan M. K.
Das Bimal K.
Gentsch John R.
Glass Roger I.
Degen Nancy
McKelvey Terry A.
The United States of America as represented by the Department of
LandOfFree
Rotavirus strain G9P11 does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Rotavirus strain G9P11, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Rotavirus strain G9P11 will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1856222