Rotavirus reassortant vaccine

Details Rotavirus reassortant vaccine Rotavirus reassortant vaccine

1998-05-11

2000-09-05

Stucker, Jeffrey

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

424 931, 424 932, 424 936, 4242151, 4352351, 435236, A61K 3912

Patent

active

061139106

ABSTRACT:
The present invention provides novel rotavirus reassortants, vaccines employing the novel reassortants and methods for their preparation and administration. One such reassortant contains the gene encoding the v.p.7 neutralization antigen of a human rotavirus. Another reassortant contains the gene encoding the v.p.4 neutralization antigen of a human rotavirus. The remaining genes are provided solely from the bovine rotavirus WC3 strain, or from both the human and bovine strains.

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