Chemistry: molecular biology and microbiology – Apparatus – Including condition or time responsive control means
Patent
1988-06-30
1991-01-29
Nucker, Christine
Chemistry: molecular biology and microbiology
Apparatus
Including condition or time responsive control means
435284, 435285, 435292, 435311, 435312, 435316, C12M 300
Patent
active
049886231
ABSTRACT:
A bio-reactor system wherein a tubular housing contains an internal circularly disposed set of blade members and a central tubular filter all mounted for rotation about a common horizontal axis and each having independent rotational support and rotational drive mechanisms. The housing, blade members and filter preferably are driven at a constant slow speed for placing a fluid culture medium with discrete microbeads and cell cultures in a discrete spatial suspension in the housing. Replacement fluid medium is symmetrically input and fluid medium is symmetrically output from the housing where the input and the output are apart of a loop providing a constant or intermittent flow of fluid medium in a closed loop.
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Schwarz Ray P.
Wolf David A.
Beisner William H.
Fein Edward K.
Manning John R.
Nucker Christine
Schlorff Russell E.
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