Rotary motor molecule V 1 -ATpase

Details Rotary motor molecule V 1 -ATpase Rotary motor molecule V 1 -ATpase

2003-10-09

2009-06-09

Kosar, Andrew D (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C530S300000, C530S324000, C424S094500

Reexamination Certificate

active

07544658

ABSTRACT:
A complex rotating in the presence of ATP, which has three A subunits, three B subunits and one D subunit constituting the V1portion of a V0V1,-ATPase.

REFERENCES:
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Yokoyama, 2000, The Journal of biological chemistry, 275, 13955-13961.
Soong, 2000, Science, 290, 1555-1558.
K. Yokoyama et al., “Thermus thermophilusmembrane-associated ATPase, Indication of a eubacterial V-type ATPase”, J. Biol. Chem., vol. 265, No. 35, pp. 21946-21950, 1990.
K. Yokoyama et al., “Isolation of prokaryotc V0V1-ATPase from a thermophilic edubacteriumThermus thermophilus”, J. Biol. Chem., vol. 269, No. 16, pp. 12248-12253, 1994.
K. Yokoyama et al., “V-ATPase ofThermus thermo philusis inactivated during ATP hydrolysis but can synthesize ATP”, J. Biol. Chem., vol. 273, No. 32, pp. 20504-20510, 1998.
K. Yokoyama et al., “V-Type H+-ATPase/synthase from a thermophilic eubacterium,Thermus thermo philus. Subunit structure and operon”, J. Biol. Chem., vol. 275, No. 18, pp. 13955-13961, 2000.
Y. Kato-Yamada et al., “Direct observation of the rotation of ε subunit in F1-ATPase”, J. Biol. Chem., vol. 273, No. 31, pp. 19375-19377, 1998.
H. Noji et al., “Direct observation of the rotation of F1-ATPase”, Nature, vol. 386, No. 6622, pp. 299-302, 1997.
H. Imamura et al., “Evidence for rotation of V1-ATPase”, Proc. Natl. Acad. Sci. U.S.A., vol. 100, No. 5, pp. 2312-2315, Mar. 2003.
K. Yokoyama et al., “Rotation of the proteolipid ring in the V-ATPase”, J. Biol. Chem., vol. 278, No. 27, pp. 24255-24258, Jul. 4, 2003.

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