Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Reexamination Certificate
2006-02-22
2009-11-03
Wilson, James O (Department: 1624)
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
Reexamination Certificate
active
07612203
ABSTRACT:
The present invention provides rosuvastatin and intermediates thereof having a low level of alkylether impurity and processes for the preparation thereof.
REFERENCES:
patent: 4231938 (1980-11-01), Monaghan et al.
patent: 4346227 (1982-08-01), Terahara et al.
patent: 4444784 (1984-04-01), Hoffman et al.
patent: 4739073 (1988-04-01), Kathawala
patent: 5006530 (1991-04-01), Angerbauer et al.
patent: 5177080 (1993-01-01), Angerbauer et al.
patent: 5202029 (1993-04-01), Haytko et al.
patent: 5260440 (1993-11-01), Hirai et al.
patent: 5354772 (1994-10-01), Kathawala
patent: 5354879 (1994-10-01), Konoike et al.
patent: RE37314 (2001-08-01), Hirai et al.
patent: 6316460 (2001-11-01), Creekmore et al.
patent: 6333198 (2001-12-01), Edmeades et al.
patent: 6777552 (2004-08-01), Niddam-Hildesheim et al.
patent: 6858618 (2005-02-01), Raza et al.
patent: 2005/0080134 (2005-04-01), Niddam-Hildesheim et al.
patent: 2005/0131066 (2005-06-01), Niddam-Hildesheim et al.
patent: 2005/0159615 (2005-07-01), Lifshitz-Liron et al.
patent: 2005/0222415 (2005-10-01), Kumar et al.
patent: 2006/0258882 (2006-11-01), Niddam-Hildesheim et al.
patent: 2007/0037979 (2007-02-01), Niddam-Hildesheim et al.
patent: 2007/0179166 (2007-08-01), Niddam-Hildesheim et al.
patent: 1 872 841 (2006-12-01), None
patent: 0 554 455 (1993-08-01), None
patent: 0 850 902 (1998-07-01), None
patent: 0 521 471 (2000-10-01), None
patent: 1 816 126 (2007-08-01), None
patent: 07 118233 (1995-05-01), None
patent: WO 00/17150 (2000-03-01), None
patent: WO 00/49014 (2000-08-01), None
patent: WO 01/60804 (2001-08-01), None
patent: WO 03/016317 (2003-02-01), None
patent: WO 03/032995 (2003-04-01), None
patent: WO 03/087112 (2003-10-01), None
patent: WO 03/097614 (2003-11-01), None
patent: WO 2004/014872 (2004-02-01), None
patent: WO 2004/052867 (2004-06-01), None
patent: WO 2005/021511 (2005-03-01), None
patent: WO 2005/023778 (2005-03-01), None
patent: WO 2005/040134 (2005-05-01), None
patent: WO 2005/056534 (2005-06-01), None
patent: WO 2005/077916 (2005-08-01), None
patent: WO 2006/035277 (2006-04-01), None
patent: WO 2006/067456 (2006-06-01), None
patent: WO 2006/079611 (2006-08-01), None
patent: WO 2006/091770 (2006-08-01), None
patent: WO 2006 100689 (2006-09-01), None
patent: WO 2006/106526 (2006-10-01), None
patent: WO 2006/136407 (2006-12-01), None
patent: WO 2006/136408 (2006-12-01), None
patent: WO 2007/007119 (2007-01-01), None
patent: WO 2007/041666 (2007-04-01), None
patent: WO 2007/099561 (2007-09-01), None
Anelli, et al., “Fast And Selective Oxidation Of Primary Alcohols To Aldehydes Or To Carboxylic Acids And Of Secondary Alcohols To Ketones Mediated By Oxoammonium Salts Under Two-Phase Conditions”,J. Org. Chem., 1987, pp. 2559-2562, vol. 52, No. 12.
Hull, et al., “Quantification Of Rosuvastatin In Human Plasma By Automated Solid-Phase Extraction Using Tandem Mass Spectrometric Detection”,Journal of Chromatography B: Biomedical Sciences&Applications, 2002, pp. 219-228, vol. 772, No. 2.
Konoike, et al. “Practical Synthesis of Chiral Synthons for the Preparation of HMG-CoA Reductase Inhibitors” J. Org. Chem., vol. 59, 1994, pp. 7849-7854.
Lenz, et al., “Tetra-N-Propylammonium Perruthenate (TPAP)-Catalysed Oxidations Of Alcohols Using Molecular Oxygen As A Co-Oxidant”,J. Chem. Soc., Perkin Trans. 1, 1997, 3291-3292.
Ley, et al.,Synthesis, 1994, 639-666.
Lipid Research Clinics Program, “The Lipid Research Clinics Coronary Primary Prevention Trial Results: I. Reduction In Incidence Of Coronary Heart Disease”,J.A.M.A., 1984, 351-74, vol. 251, No. 3.
Scandinavian Simvastatin Survival Study Group, “Randomised Trial Of Cholesterol Lowering In 4444 Patients With Coronary Heart Disease: The Scandinavian Survival Study (4s)”,The Lancet, 1994, pp. 1383-1389, vol. 344.
Snyder, et al.,Introduction To Modern Liquid Chromatography, 2nd ed., John Wiley & Sons: New York, 1979, pp. 549, 552, 571-572.
Strobel, et al.,Chemical Instrumentation: A Systematic Approach, 3rded., Wiley & Sons: New York, 1989, pp. 391-393, 879, 894, 922, 924-925, 953.
Wantanabe, et al., “Synthesis And Biological Antivity Of Methanesulfonamide Pyramidine-And N-Methanesulfonyl Pyrrole-Substituted 3,5-Dihydroxy-6-Heptenoates, A Novel Series Of HMG-CoA Reductase Inhibitors”,Bioorganic&Medicinal Chemistry, 1997, pp. 437-444, vol. 5, No. 2.
Witztum, “Chapter 36: Drugs Used In The Treatment Of Hyperlipoproteinemias”,Goodman&Gilman's The Pharmacological Basis Of Therapeutics, 9thed., pp. 875-897.
Szantay, et al., “Synthesis of Novel HMG-CoA Reductase Inhibitors, Naphthalene Analogs of Mevinolin”, Liebigs Ann. Chem., 1992, pp. 145-157.
Ohrlein, et al., “Chemo-Enzymatic Approach to Statin Side-Chain Building Blocks”, Adv. Synth. Catal., 2003, pp. 713-715, vol. 345.
Greene, “Protective Groups in Organic Synthesis”, John Wiley & Sons, Inc., 1981.
Tetrahedron, 1997, pp. 10659-10670, vol. 53 (31).
Mehta, T.N. et al, Determination Of Rosuvastatin In The Presence of Its Degradation Products By A Stability-Indicating LC Method, Journal of AOAC International, AOAC International, Arlington, VA, US, vol. 88, No. 4, Jul. 2005, pp. 1142-1147, XP008066428.
Sane, R.T. et al, Determination of Rosuvastatin Calcium In Its Bulk Drug And Pharmaceutical Preparations By High-Performance Thin-Layer Chromatography: JPC. Journal of Planar Chromatography, Moder TLC, Huethig, Heidelberg, DE, vol. 18, No. 103, May 2005, p. 194-198, XP008066430.
Balanov Anna
Niddam-Hildesheim Valerie
Shenkar Natalia
Jarrell Noble
Kenyon & Kenyon LLP
Teva Pharmaceutical Industries Ltd.
Wilson James O
LandOfFree
Rosuvastatin and salts thereof free of rosuvastatin... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Rosuvastatin and salts thereof free of rosuvastatin..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Rosuvastatin and salts thereof free of rosuvastatin... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4071222