Rose-hip formulations as anti-inflammatory natural medicine for

Details Rose-hip formulations as anti-inflammatory natural medicine for Rose-hip formulations as anti-inflammatory natural medicine for

1998-04-17

2000-02-15

Kulkosky, Peter F.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Conjugate or complex

514825, 426655, A61K 3578

Patent

active

060249609

ABSTRACT:
A formulation having a rose hip concentrate is used to treat and/or alleviate the symptoms associated with inflammation including arthritis or to prevent development of arthritis. The rose hip concentrate has a high vitamin content relative to conventionally dried material, and is shown, in vitro, to inhibit the chemotaxis and oxidative burst response of human peripheral blood inflammatory cells, as well as the chemotaxis of monocytes. The formulation, in vivo, was found to inhibit chemotaxis of human peripheral blood inflammatory cells and to reduce the level of C-reactive protein, to alleviate pain and reduce inflammation in patients with arthritis.

REFERENCES:
patent: 4774229 (1988-09-01), Jordan
patent: 5744187 (1998-04-01), Gaynor
CA104: 174649 F. Morishige Nissan Chem. Ind. Ltd. Japan Dec. 11, 1985.
CA 101:136 B. Spilker et al 1984 (35)(4) 593-605.
Fabad.J.Pharm. Sci. 15, 121-131, 1990 S.Kurucu et al.

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