Room temperature storable immunoglobulin preparation for intrave

Details Room temperature storable immunoglobulin preparation for intrave Room temperature storable immunoglobulin preparation for intrave

1998-10-23

2000-12-12

Saunders, David

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Free from infectious agents

4241771, 5303901, 5303905, 530414, 530415, 530416, 530421, A61K 39395

Patent

active

061594717

ABSTRACT:
A method for producing an immunoglobulin preparation for intravenous injection, which comprises the steps of: fractionating an immunoglobulin-containing solution with 4 to 10 w/v % of polyethylene glycol having a molecular weight of from 1,000 to 10,000, at a pH value of from 4.5 to 6.5, an ionic strength of from 0.0001 to 0.1 M and a temperature of from 0 to 4.degree. C. to recover a supernatant fraction; and concentrating the supernatant fraction at a pH of from 3.5 to 5.0.

REFERENCES:
patent: 4874708 (1989-10-01), Makula et al.
patent: 4876088 (1989-10-01), Hirao et al.
patent: 5132406 (1992-07-01), Uemura et al.
patent: 5177194 (1993-01-01), Sarno et al.
Y. Uemura et al. "Inactivation and Elimination of Viruses During Preparation of Human Intravenous Immunoglobulin" Vox Sanguinis, vol. 67, No. 3, Oct. 1994, pp. 246-254.
Database WPI, Week 8943, Derwent Publications Ltd., London, GB; AN 89-312793 XP-002090955 & JP 01 230533 A (The Green Cross Corporation), Sep. 14, 1989.
Database WPI, Week 9518, Derwent Publications Ltd., London, GB; AN 95-136796 XP002090956 & JP 07 061935 A (The Green Cross Corporation), Mar. 7, 1995).
Database WPI, Week 9625, Derwent Publications Ltd., London, GB; AN 96-246917 XP002090957 & JP 08 099900 A (The Green Cross Corporation), Apr. 16, 1996).

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