Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Patent
1979-01-18
1980-07-08
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
A61K 3166
Patent
active
042117755
ABSTRACT:
On feeding ronnel, i.e., O,O-dimethyl O-(2,4,5-trichlorophenyl)phosphorothioate, to livestock and poultry selected from cloven hoof ruminant animals, swine and poultry substantially every day for at least about 3 to about 28 days depending on the animal, and more preferably for a longer period through growth and/or fattening feeding cycles or during maintenance periods, in an effective amount at a dosage below the parasiticidal level in the range of about 0.5 to about 2.5 milligrams of ronnel per kilogram (mg/kg) of body weight per day, a nutritional response is obtained exhibited as faster growth of the livestock and poultry; fiber production, such as wool in sheep, is increased; the production of milk in lactating animals is increased; and, moreover, the feed conversion efficiency of the animal is substantially improved. The ronnel is provided for oral ingestion by the animal on a voluntary basis upon incorporating sufficient ronnel into a balanced feed diet or a component thereof to provide about 0.5 to about 2.5 mg of ronnel per kg of body weight per animal per day on average and substantially every day during the period of nutritional response promotion treatment, prepared feeds typically containing from about 3 to about 190 grams of ronnel per ton of feed (dry matter basis) depending on the age and type of animal. For range-fed animals, the ronnel is conveniently incorporated in a mineral, protein or energy type feed additive supplement.
REFERENCES:
patent: 2811480 (1957-10-01), Norris et al.
Journal of Animal Science, #4, 1975, 743-749.
Journal of Economic Entomology, vol. 53, No. 4, 541-546.
Brookens Ronald G.
Schilling Edward E.
The Dow Chemical Company
Waddell Frederick E.
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