Chemistry: molecular biology and microbiology – Apparatus – Mutation or genetic engineering apparatus
Patent
1989-04-27
1990-03-27
Yeung, James C.
Chemistry: molecular biology and microbiology
Apparatus
Mutation or genetic engineering apparatus
435296, 366233, C12M 300
Patent
active
049120581
ABSTRACT:
A roller bottle is provided with provision for increased internal surface area for cell growth by the use of a foamed, textured or woven liner or sleeve inserted into the bottle prior to use. The sleeve may be used in a single use roller bottle or a multiple use roller bottle. With the latter, the sleeve is discarded, the bottle sterilized, and a new sleeve or liner is inserted. The interstices of the foamed, textured or woven surface has the effect of increasing the actual surface area available for culturing cells in each single roller bottle, thus making the roller bottle of the invention cost effective.
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Gray Harry E.
Mussi Edward F.
Becton Dickinson and Company
Grindle Robert P.
Yeung James C.
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