Roller bottle

Chemistry: molecular biology and microbiology – Apparatus – Mutation or genetic engineering apparatus

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Details

435296, 366233, C12M 300

Patent

active

049120581

ABSTRACT:
A roller bottle is provided with provision for increased internal surface area for cell growth by the use of a foamed, textured or woven liner or sleeve inserted into the bottle prior to use. The sleeve may be used in a single use roller bottle or a multiple use roller bottle. With the latter, the sleeve is discarded, the bottle sterilized, and a new sleeve or liner is inserted. The interstices of the foamed, textured or woven surface has the effect of increasing the actual surface area available for culturing cells in each single roller bottle, thus making the roller bottle of the invention cost effective.

REFERENCES:
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patent: 3941661 (1976-03-01), Noteboom
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patent: 4046138 (1977-09-01), Libman et al.
patent: 4065359 (1977-12-01), Hurni
patent: 4289248 (1981-09-01), Lynn
patent: 4314030 (1982-02-01), Habich
patent: 4317886 (1982-03-01), Johnson et al.
patent: 4337104 (1982-06-01), Lynn
patent: 4600694 (1986-07-01), Clyde
patent: 4689301 (1987-08-01), Adet et al.
patent: 4829004 (1989-05-01), Varani et al.

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