Role for GLP-1 to mediate responses to disparate stressors

Details Role for GLP-1 to mediate responses to disparate stressors Role for GLP-1 to mediate responses to disparate stressors

2008-05-27

2008-05-27

O'Hara, Eileen (Department: 1649)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C530S300000

Reexamination Certificate

active

07378385

ABSTRACT:
GLP-1 and GLP-1 receptor antagonists have been found to have a sedative or anxiolytic effect on the mammalian central nervous system. Conversely, GLP-1 and GLP-1 receptor agonists increase nervous system activity and the stress response. The invention relates, in one aspect, to the use of GLP-1 agonists and antagonists to modulate the stress response in a mammal. In an aspect GLP-1 and GLP-1 receptor antagonists are used to treat stress-related disorders.

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