Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1979-10-22
1981-02-17
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
424 17, A01N 4340, A01N 2500
Patent
active
042515360
ABSTRACT:
Anticoagulant compounds have been extensively used as rodenticides during the last 20 years. In most parts of the world rats have become resistant to anticoagulants. This circumstance seriously limits the usefulness of anticoagulant rodenticides, and gives rise to the need for a novel effective rodenticide. 6-Aminonicotinamide and 6-aminonicotinohydroxamic acid have been found to be potent rodent poisons, moreso in the rat than in the mouse. They are much less toxic to other species, such as the dog. An important feature of these compounds as rodenticides is the fact that nicotinamide is an excellent and complete antidote, even when administered after toxic symptoms have appeared. 6-Aminonicotinamide and 6-aminonicotinohydroxamic acid do not have objectionable taste or odor, and hence can be mixed with food products as edible carriers. These compounds are single-dose rodenticides in that the ingestion of only a few milligrams is fatal to a rodent, resulting in depth which occurs a few days after ingestion of the poison. Unlike the anticoagulant poisons, the mechanism of action of 6-aminonicotinamide and 6-aminonicotinohydroxamic acid is such that the development of resistance to them is virtually impossible.
REFERENCES:
Chem. Abst.-9th Collective Index page 33760CS.
Pascal Edward E.
Robinson Douglas W.
LandOfFree
Rodenticides comprising 6-aminonicotinamide or 6-aminonicotinohy does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Rodenticides comprising 6-aminonicotinamide or 6-aminonicotinohy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Rodenticides comprising 6-aminonicotinamide or 6-aminonicotinohy will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2262496